Kaplonyi G, Zimmerman I, Frenyo A D, Farkas T, Nemes G
National Institute of Traumatology, Budapest, Hungary.
Injury. 1988 Jul;19(4):267-72. doi: 10.1016/0020-1383(88)90043-5.
Fibrin adhesive proved to be useful in the reattachment of chondral and osteochondral fragments. Its use is based on sound biological principles. It offers a number of advantages over internal fixation; it causes no further damage to the cartilage, even small chondral fragments can be reattached and a second operation for the removal of metalwork is unnecessary. Its bonding strength provides only contact stability, so that immobilization in plaster for 3 weeks is always necessary. In the last 5 years we have used fibrin adhesive in 28 patients for the fixation of 39 chondral or osteochondral fragments. Of these, 26 cases were followed up for periods of 6 months to 5 years. Twelve patients were examined arthroscopically; 9 of them showed complete healing of the fragments, and only 3 slight localized degenerative changes. In 15 cases we were able to see radiological healing. All except two showed union of the fragments and restoration of the joint surface. In view of our results fibrin adhesive can be recommended for the operative management of cartilage injuries.
纤维蛋白粘合剂被证明在软骨和骨软骨碎片的重新附着方面很有用。它的使用基于合理的生物学原理。与内固定相比，它有许多优点；它不会对软骨造成进一步损伤，即使是小的软骨碎片也能重新附着，并且无需进行二次手术来取出金属固定物。其粘结强度仅提供接触稳定性，因此总是需要用石膏固定3周。在过去5年中，我们在28例患者中使用纤维蛋白粘合剂固定了39块软骨或骨软骨碎片。其中，26例患者随访了6个月至5年。12例患者接受了关节镜检查；其中9例碎片完全愈合，只有3例有轻微的局部退行性改变。在15例患者中，我们能够看到放射学愈合。除两例外，所有患者均显示碎片愈合且关节面恢复。鉴于我们的结果，纤维蛋白粘合剂可推荐用于软骨损伤的手术治疗。
