Madani Azam S, Ahrari Farzaneh, Nasiri Farideh, Abtahi Mostafa, Tunér Jan
Cranio. 2014 Jan;32(1):38-44. doi: 10.1179/0886963413Z.0000000004.
This study investigated the efficacy of low-level laser therapy (LLLT) for the management of temporomandibular joint (TMJ) osteoarthritis.
In a double-blind clinical trial, 20 patients with TMJ osteoarthritis were randomly divided into laser and placebo groups. The patients in the laser group received irradiation from an 810 nm low-level laser (Peak power 80 W, average power 50 mW, 1500 Hz, 1 micro s pulse width, 120 seconds, 6 J, 3.4 J/cm(2) per point), which was applied on four points around the TMJs and on painful muscles three times a week for 4 weeks. In the placebo group, the treatment was the same as that in the laser group, but with laser simulation. The patients were evaluated before laser therapy (T1), after 6 (T2) and 12 (T3) laser applications and 1 month after the last application (T4), and the amount of mouth opening and the pain intensity were recorded.
No significant differences were found in mouth opening either between the study groups or between the different evaluation times in each group (P>0.05). There was no significant difference in pain symptoms of the masticatory muscles and TMJ between the laser and the placebo groups (P>0.05), but some significant within-group improvements were present for Visual Analogue Scale (VAS) scores of the body of the masseter and TMJ in both groups.
LLLT using the present laser parameters was no more effective than the placebo treatment for reducing pain and improving mouth opening in patients with TMJ osteoarthritis.
本研究调查了低强度激光疗法(LLLT)治疗颞下颌关节(TMJ)骨关节炎的疗效。
在一项双盲临床试验中,20例TMJ骨关节炎患者被随机分为激光组和安慰剂组。激光组患者接受810 nm低强度激光照射(峰值功率80 W,平均功率50 mW,1500 Hz,1微秒脉冲宽度,120秒,6 J,每点3.4 J/cm²),该激光应用于TMJ周围的四个点以及疼痛肌肉上,每周3次,共4周。在安慰剂组中,治疗与激光组相同,但采用激光模拟。在激光治疗前(T1)、6次(T2)和12次(T3)激光照射后以及最后一次照射后1个月(T4)对患者进行评估,并记录开口度和疼痛强度。
研究组之间以及每组不同评估时间之间的开口度均无显著差异(P>0.05)。激光组和安慰剂组咀嚼肌和TMJ的疼痛症状无显著差异(P>0.05),但两组咬肌主体和TMJ的视觉模拟量表(VAS)评分在组内均有一些显著改善。
使用当前激光参数的LLLT在减轻TMJ骨关节炎患者的疼痛和改善开口度方面并不比安慰剂治疗更有效。