Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Ling-Ling Road, Shanghai 200032, China.
Org Lett. 2014 Apr 4;16(7):2030-3. doi: 10.1021/ol500612n. Epub 2014 Mar 24.
A novel Cu-mediated trifluoromethylthiolation of diazo compounds has been developed that provides a convenient synthetic route for the efficient α-trifluoromethylthiolation of simple esters under mild reaction conditions. The reaction is typically carried out at room temperature, and water could be used to promote the reaction.
发展了一种新型的铜介导的重氮化合物三氟甲基化反应，为温和条件下简单酯类化合物的高效α-三氟甲基化提供了一种方便的合成途径。该反应通常在室温下进行，并且可以使用水来促进反应。
