Mary D. Allen Laboratory for Vision Research, Doheny Eye Institute, Departments of Ophthalmology and Cell & Neurobiology, Keck School of Medicine of the University of Southern California, 1355 San Pablo St., DVRC 405, 90033, Los Angeles, CA, USA,
Adv Exp Med Biol. 2014;801:49-56. doi: 10.1007/978-1-4614-3209-8_7.
Macaca, Callithrix jacchus marmoset monkey, Pan troglodytes chimpanzee and human retinas were examined to define if short wavelength (S) cones share molecular markers with L&M cone or rod photoreceptors. S cones showed consistent differences in their immunohistochemical staining and expression levels compared to L&M cones for "rod" Arrestin1 (S-Antigen), "cone" Arrestin4, cone alpha transducin, and Calbindin. Our data verify a similar pattern of expression in these primate retinas and provide clues to the structural divergence of rods and S cones versus L&M cones, suggesting S cone retinal function is "intermediate" between them.
猕猴、食蟹猴狨猴和人视网膜被检查以确定短波长（S）视锥细胞是否与 L&M 视锥细胞或视杆细胞感受器共享分子标记物。与 L&M 视锥细胞相比，S 视锥细胞在免疫组织化学染色和表达水平上表现出一致的差异，用于“视杆” arrestin1（S-抗原）、“视锥” arrestin4、视锥 alpha 转导蛋白和钙结合蛋白。我们的数据验证了这些灵长类动物视网膜中相似的表达模式，并为视杆细胞和 S 视锥细胞与 L&M 视锥细胞的结构分化提供了线索，表明 S 视锥细胞的视网膜功能介于它们之间。
