免疫反应性磷脂酶A2在急性胰腺炎中的诊断价值
Diagnostic value of immunoreactive phospholipase A2 in acute pancreatitis.
作者信息
Malfertheiner P, Nevalainen T, Uhl W, Schädlich H, Büchler M
机构信息
Department of Gastroenterology, University of Ulm.
出版信息
Klin Wochenschr. 1989 Feb 1;67(3):183-5. doi: 10.1007/BF01711350.
In a prospective clinical trial 85 patients with acute pancreatitis were analysed for serum total amylase, pancreatic amylase, pancreatic lipase, trypsin, elastase 1, and immunoreactive phospholipase A2 (IR-PLA2). The diagnostic sensitivity of serum IR-PLA2 was comparable to that of serum total amylase, pancreatic amylase, and trypsin. The specificity of IR-PLA2 is superior to that of serum total amylase determination due to the fact that the IR-PLA2 determination is based on an antibody against human pancreatic PLA2.
在一项前瞻性临床试验中，对85例急性胰腺炎患者的血清总淀粉酶、胰腺淀粉酶、胰腺脂肪酶、胰蛋白酶、弹性蛋白酶1和免疫反应性磷脂酶A2（IR-PLA2）进行了分析。血清IR-PLA2的诊断敏感性与血清总淀粉酶、胰腺淀粉酶和胰蛋白酶相当。由于IR-PLA2测定基于抗人胰腺PLA2的抗体，其特异性优于血清总淀粉酶测定。
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