Tompkins Ronald G
From the Department of Surgery, Massachusetts General Hospital, and Harvard Medical School, Boston, MA.
Ann Surg. 2015 Feb;261(2):263-8. doi: 10.1097/SLA.0000000000000623.
This review explores the series of published analyses from Massachusetts General Hospital to better understand how changes in medical specialization of burn medicine likely enabled the most important increase in survival from burns in the past 70 years.
Seventy years ago, survival from the most serious burn injuries was not possible even in the most advanced countries until critical advances were introduced. Insights into those few medical advances that actually impacted survival might be better understood from the consideration of a continuous series of survival analyses over 7 decades at Massachusetts General Hospital.
Mortality data from previously reported probit and logit analyses from thousands of patients treated at Massachusetts General Hospital were reviewed. A comparison of mortality from these prior mortality analyses from a more recent multicenter study and a national data set was performed.
The only giant leap forward in survival occurred during the 1970s, with no improvement during either the preceding or subsequent 30-year intervals. Despite the many modern advances that have been added to the care of these patients since 1984, although these may have represented medical progress, these advances did not impact survival.
Survival rates from burn injury may have been maximized by current treatment approaches within medical centers of excellence in burn medicine. Further efforts to improve the quality of life of survivors of burn injury should ultimately have very favorable impact upon the long-term outcomes in these patients who now survive such devastating injuries.
本综述探讨了麻省总医院发表的一系列分析,以更好地理解烧伤医学专业的变化如何可能促成了过去70年中烧伤存活率最重要的提升。
70年前,即使在最先进的国家,除非引入关键进展,否则最严重的烧伤伤者也无法存活。通过考虑麻省总医院70多年来一系列连续的生存分析,或许能更好地理解那些真正影响存活率的医学进展。
回顾了麻省总医院此前对数以千计患者进行的概率分析和逻辑分析中报告的死亡率数据。将这些先前死亡率分析的死亡率与最近的一项多中心研究和一个全国数据集进行了比较。
存活率唯一的巨大飞跃发生在20世纪70年代,在之前和之后的30年期间均无改善。尽管自1984年以来,这些患者的护理增加了许多现代进展,尽管这些可能代表了医学进步,但这些进展并未影响存活率。
在烧伤医学卓越中心,当前的治疗方法可能已使烧伤损伤的存活率最大化。进一步努力改善烧伤幸存者的生活质量,最终应会对这些如今在如此严重损伤中存活下来的患者的长期预后产生非常有利的影响。