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人参多糖对链脲佐菌素诱导的糖尿病小鼠的降血糖和抗氧化活性。

Anti-hyperglycemic and anti-oxidative activities of ginseng polysaccharides in STZ-induced diabetic mice.

机构信息

Jilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, PR China.

出版信息

Food Funct. 2014 May;5(5):845-8. doi: 10.1039/c3fo60326a.

DOI:10.1039/c3fo60326a
PMID:24671219
Abstract

Neutral (WGPN) and acidic (WGPA) polysaccharides were fractionated from ginseng polysaccharide. WGPN and WGPA decreased fasting blood glucose by different manners of administration. Intra-gastric administration of WGPA showed a marked hypoglycemic effect, which may be related to its anti-oxidative activity. The results indicated that WGPA may have anti-diabetic potential.

摘要

从人参多糖中分离出中性（WGPN）和酸性（WGPA）多糖。WGPN 和 WGPA 通过不同的给药方式降低空腹血糖。WGPA 的胃内给药显示出显著的降血糖作用，这可能与其抗氧化活性有关。结果表明，WGPA 可能具有抗糖尿病潜力。

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