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近年来,植物系统生物学中代谢组数据库的发展取得了进展。

Recent progress in the development of metabolome databases for plant systems biology.

机构信息

RIKEN Plant Science Center Yokohama, Kanagawa, Japan.

出版信息

Front Plant Sci. 2013 Apr 4;4:73. doi: 10.3389/fpls.2013.00073. eCollection 2013.

Abstract

Metabolomics has grown greatly as a functional genomics tool, and has become an invaluable diagnostic tool for biochemical phenotyping of biological systems. Over the past decades, a number of databases involving information related to mass spectra, compound names and structures, statistical/mathematical models and metabolic pathways, and metabolite profile data have been developed. Such databases complement each other and support efficient growth in this area, although the data resources remain scattered across the World Wide Web. Here, we review available metabolome databases and summarize the present status of development of related tools, particularly focusing on the plant metabolome. Data sharing discussed here will pave way for the robust interpretation of metabolomic data and advances in plant systems biology.

摘要

代谢组学作为一种功能基因组学工具得到了极大的发展,并且已经成为生物系统生化表型分析的一种非常有价值的诊断工具。在过去的几十年中,已经开发了许多涉及质谱、化合物名称和结构、统计/数学模型和代谢途径以及代谢物图谱数据相关信息的数据库。这些数据库相互补充,支持该领域的高效发展,尽管数据资源仍然分散在万维网上。在这里,我们回顾了现有的代谢组学数据库,并总结了相关工具的发展现状,特别是重点关注植物代谢组学。这里讨论的数据共享将为代谢组学数据的稳健解释和植物系统生物学的发展铺平道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51f9/3616245/143afb3db80c/fpls-04-00073-g001.jpg

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