Bacon Simon L, Campbell Tavis S, Arsenault André, Lavoie Kim L
Montreal Behavioural Medicine Centre, Research Centre, Hopital du Sacre-Coeur de Montreal, 5400 Boulevard Gouin Ouest, Montréal, QC, Canada H4J 1C5 ; Department of Exercise Science, Concordia University, 7141 Sherbrooke Street West, Montreal, QC, Canada H4B 1R6 ; Centre de Readaptation Jean-Jacques-Gauthier, Hopital du Sacre-Coeur de Montréal, 5400 Boulevard Gouin Ouest, Montréal, QC, Canada H4J 1C5 ; Research Centre, Montréal Heart Institute, 5000 rue Belanger, Montréal, QC, Canada H1T 1C8.
Montreal Behavioural Medicine Centre, Research Centre, Hopital du Sacre-Coeur de Montreal, 5400 Boulevard Gouin Ouest, Montréal, QC, Canada H4J 1C5 ; Department of Psychology, University of Calgary, 2500 University Drive NW, Calgary, AL, Canada T2N 1N4.
Int J Hypertens. 2014;2014:953094. doi: 10.1155/2014/953094. Epub 2014 Feb 2.
Background. Studies assessing the association between psychological factors and hypertension have been equivocal, which may reflect limitations in the assessment of psychological factors. Purpose. To assess the relationship between mood and anxiety disorders, measured using a psychiatric interview, and 1-year incident hypertension. Methods. 197 nonhypertensive individuals undergoing exercise stress testing at baseline provided follow-up data at 1 year. Baseline assessments included a structure psychiatric interview (PRIME-MD), physician diagnosis of hypertension, and measured blood pressure. At follow-up, hypertension status was assessed via self-reported physician diagnosis. Results. Having an anxiety disorder was associated with a 4-fold increase in the risk of developing hypertension (adjusted OR = 4.14, 95% CIs = 1.18-14.56). In contrast, having a mood disorder was not associated with incident hypertension (adjusted OR = 1.21, 95% CIs = 0.24-5.86). Conclusions. There are potential mechanisms which could explain our differential mood and anxiety findings. The impact of screening and treatment of anxiety disorders on hypertension needs to be explored.
背景。评估心理因素与高血压之间关联的研究结果并不明确，这可能反映出心理因素评估方面存在局限性。目的。使用精神科访谈来评估情绪和焦虑障碍与1年新发高血压之间的关系。方法。197名在基线时接受运动压力测试的非高血压个体在1年后提供了随访数据。基线评估包括结构化精神科访谈（PRIME-MD）、医生对高血压的诊断以及测量血压。在随访时，通过自我报告的医生诊断来评估高血压状态。结果。患有焦虑障碍与患高血压风险增加4倍相关（校正比值比=4.14，95%置信区间=1.18-14.56）。相比之下，患有情绪障碍与新发高血压无关（校正比值比=1.21，95%置信区间=0.24-5.86）。结论。存在一些潜在机制可以解释我们在情绪和焦虑方面的不同研究结果。需要探索焦虑障碍的筛查和治疗对高血压的影响。
