Li Cangtuo, Hou Qiqi, Han Quanle, Zhang Yuan, Yu Jie, Wu Jianmei, Yang Hui, Wang Nan, Zhang Jiawei, Li Kangbo
Department of Intervention, Tangshan Gongren Hospital, Tangshan, People's Republic of China.
Hebei Medical University, Shijiazhuang, People's Republic of China.
Int J Gen Med. 2024 Dec 4;17:5807-5815. doi: 10.2147/IJGM.S480357. eCollection 2024.
The present study assessed the correlation between anxiety and depression in young and middle-aged Chinese patients with coronary artery disease (CAD).
This study included 313 patients diagnosed with premature CAD at the Department of Cardiology between January and July 2023. The Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) was used as a standardized scale to assess mental health symptoms. A binary logistic regression model (backward) was used to analyze the correlation between anxiety and depression in premature CAD.
Anxiety was observed in 154 persons with a prevalence of 49.20%, with a median SAS score of 53.0 (52.00-54.00). Depression was observed in 91 patients, with a prevalence of 29.07%, with a median SDS score was 55.00 (54.00-57.00). A total of 63 (20.13%) patients had comorbid anxiety and depression. Multivariate logistic regression analysis revealed that anxiety was positively associated with severe coronary artery stenosis, systolic blood pressure (SBP), body mass index, and snoring. However, it is negatively associated with high-income levels. Depression was positively associated with age, severe coronary artery stenosis, and snoring. However, it was negatively associated with SBP. Comorbid anxiety and depression were positively associated with age, severe coronary artery stenosis, and snoring.
For the first time, we investigated the prevalence and correlators of anxiety and depression in premature CAD. Therefore, the correlators of emotional status should be routinely evaluated in both primary and specialized care services.
本研究评估了中国中青年冠心病（CAD）患者焦虑与抑郁之间的相关性。
本研究纳入了2023年1月至7月在心脏病科诊断为早发CAD的313例患者。采用zung自评焦虑/抑郁量表（SAS/SDS）作为评估心理健康症状的标准化量表。采用二元逻辑回归模型（向后法）分析早发CAD患者焦虑与抑郁之间的相关性。
154人存在焦虑，患病率为49.20%，SAS评分中位数为53.0（52.00 - 54.00）。91例患者存在抑郁，患病率为29.07%，SDS评分中位数为55.00（54.00 - 57.00）。共有63例（20.13%）患者合并焦虑和抑郁。多因素逻辑回归分析显示，焦虑与严重冠状动脉狭窄、收缩压（SBP）、体重指数和打鼾呈正相关。然而，它与高收入水平呈负相关。抑郁与年龄、严重冠状动脉狭窄和打鼾呈正相关。然而，它与SBP呈负相关。合并焦虑和抑郁与年龄、严重冠状动脉狭窄和打鼾呈正相关。
我们首次调查了早发CAD患者焦虑和抑郁的患病率及相关因素。因此，在初级和专科护理服务中应常规评估情绪状态的相关因素。
