一名患有热带痉挛性截瘫的牙买加患者脑脊液中I型人类嗜T细胞病毒毒株与I型人类嗜T细胞病毒原型的比较。
Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis with a prototype human T-cell lymphotropic virus type I.
作者信息
Sarin P S, Rodgers-Johnson P, Sun D K, Thornton A H, Morgan O S, Gibbs W N, Mora C, McKhann G, Gajdusek D C, Gibbs C J
机构信息
Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, MD 20892.
出版信息
Proc Natl Acad Sci U S A. 1989 Mar;86(6):2021-5. doi: 10.1073/pnas.86.6.2021.
The isolation and characterization of a human T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is described. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia but is not identical to this prototype HTLV-I as seen by restriction enzyme mapping.
本文描述了从一名患有热带痉挛性截瘫的牙买加患者的脑脊液中分离和鉴定出一种与I型人类嗜T细胞逆转录病毒（HTLV-I）相关的人类嗜T细胞逆转录病毒。通过电子显微镜观察，该病毒分离株是典型的C型逆转录病毒，与从成人T细胞白血病患者中分离出的HTLV-I原型相关，但通过限制性酶切图谱分析可知，它与该HTLV-I原型并不相同。
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