East Mediterr Health J. 2013 Nov;19(11):953-9.
In Morocco, acute Atractylis gummifera L. poisoning represents the leading cause of death by plant poisoning especially for children. All cases received in the Moroccan poison control centre from January 1981 to December 2009 (n = 467) were included in a retrospective study of the characteristics and risk factors of A. gummifera L. poisoning. The most vulnerable age group was children (63.4% of cases). Most cases were due to accidental exposure (75.5%), but some were from therapeutic use (18.1%) or attempted abortion (7.4%). Patients presented with moderate poison severity signs (grade 2) in 22.3% of cases or severe signs (grade 3) in 21.0%. The mortality rate was 39.2%. The majority of deaths (81.1%) occurred in children aged < 15 years following accidental exposure. Multivariate logistic regression analysis revealed that risk factors for mortality were coma (OR = 20.5); hepatitis (OR = 52.7) and rural residence (OR = 7.26), while gastric decontamination was a protector factor (OR = 0.26).
在摩洛哥，急性苍术属植物中毒是植物中毒导致死亡的主要原因，尤其是儿童。1981 年 1 月至 2009 年 12 月期间，摩洛哥中毒控制中心收治的所有病例（n=467）均纳入苍术属植物中毒的特征和危险因素的回顾性研究。最脆弱的年龄组是儿童（63.4%的病例）。大多数病例是意外暴露引起的（75.5%），但有些是治疗用途（18.1%）或堕胎企图（7.4%）。22.3%的患者出现中度中毒体征（2 级），21.0%的患者出现严重中毒体征（3 级）。死亡率为 39.2%。大多数死亡（81.1%）发生在意外暴露后年龄<15 岁的儿童中。多变量逻辑回归分析显示，死亡的危险因素为昏迷（OR=20.5）、肝炎（OR=52.7）和农村居住（OR=7.26），而胃去污是保护因素（OR=0.26）。
