Peyrot M, Xu Y, Rubin R R
Department of Sociology, Loyola University Maryland, Baltimore, MD, USA.
Diabet Med. 2014 Oct;31(10):1237-44. doi: 10.1111/dme.12453. Epub 2014 Apr 18.
To develop and validate a short form of the 54-item Diabetes Medication System Rating Questionnaire that maintains the domains and performance characteristics of the long-form questionnaire.
Data from the Diabetes Medication System Rating Questionnaire validation study were analysed to select items representing the nine scales (convenience, negative events, interference, self-monitoring of blood glucose burden, efficacy, social burden, psychological well-being, treatment satisfaction and treatment preference). The resulting 20-item Diabetes Medication System Rating Questionnaire Short-Form was administered online, with validated criterion measures of treatment satisfaction and medication adherence, with a retest within 2 weeks. Participants were US adults (N = 413) with Type 2 diabetes using oral agents alone; insulin by syringe and/or pen with or without oral agents; or glucagon-like peptide-1 agents. Most participants (82%) completed the retest.
The median inter-item agreement of scales was 0.76 and the total composite (mean of all items except treatment preference) was 0.88. The median test-retest reliability of scales was 0.86, and of the total composite was 0.95. All statistically significant correlations between Diabetes Medication System Rating Questionnaire Short-Form scales and criterion measures of treatment satisfaction and adherence were in the expected direction. The median correlation of the Diabetes Medication System Rating Questionnaire Short-Form with corresponding criterion measures of treatment satisfaction was 0.59; the mean correlation of the same Diabetes Medication System Rating Questionnaire Short-Form measures with adherence was 0.42. The Diabetes Medication System Rating Questionnaire Short-Form scales were more powerful predictors of adherence than were the criterion measures of treatment satisfaction. The Diabetes Medication System Rating Questionnaire Short-Form scales differentiated between those taking different medications and between those using different insulin delivery devices.
This study suggests that the Diabetes Medication System Rating Questionnaire Short-Form provides a comprehensive set of measures with acceptable reliability and validity and a reduced burden of administration.
开发并验证54项糖尿病药物治疗系统评分问卷的简版，使其保留长版问卷的各领域内容及性能特征。
对糖尿病药物治疗系统评分问卷验证研究的数据进行分析，以选择代表九个量表（便利性、负面事件、干扰、血糖自我监测负担、疗效、社会负担、心理健康、治疗满意度和治疗偏好）的条目。由此产生的20项糖尿病药物治疗系统评分问卷简版通过在线方式进行施测，并采用经过验证的治疗满意度和药物依从性标准测量方法，在2周内进行重测。参与者为仅使用口服药物、使用注射器和/或笔注射胰岛素（无论是否联合口服药物）或使用胰高血糖素样肽-1药物的美国成年2型糖尿病患者。大多数参与者（82%）完成了重测。
各量表的条目间中位数一致性为0.76，总综合得分（除治疗偏好外所有条目的平均值）为0.88。各量表的重测信度中位数为0.86，总综合得分的重测信度为0.95。糖尿病药物治疗系统评分问卷简版各量表与治疗满意度和依从性标准测量方法之间所有具有统计学意义的相关性均符合预期方向。糖尿病药物治疗系统评分问卷简版与相应治疗满意度标准测量方法的中位数相关性为0.59；同一糖尿病药物治疗系统评分问卷简版测量方法与依从性的平均相关性为0.42。糖尿病药物治疗系统评分问卷简版量表比治疗满意度标准测量方法更能有力地预测依从性。糖尿病药物治疗系统评分问卷简版量表能够区分服用不同药物的患者以及使用不同胰岛素给药装置的患者。
本研究表明，糖尿病药物治疗系统评分问卷简版提供了一套全面的测量方法，具有可接受的信度和效度，且管理负担减轻。
