Hu Jian-bin, Jin Mei, Chen En-guo, Sun Xiao-nan
Department of Radiation Oncology, Sir Run Run Shaw Hospital of Zhejiang University Medical School, No, 3 Qingchun East Road, 310016 Hangzhou, Zhejiang Province, China.
World J Surg Oncol. 2014 Mar 27;12:68. doi: 10.1186/1477-7819-12-68.
Metastatic carcinoma to the nasopharynx is extremely rare, and few cases have been reported in the literature. In the present report, we describe the case of a patient with a mass in the nasopharynx found by bronchoscopy. Our patient was a 61-year-old man receiving multiple bronchoscopy intervention therapies for advanced lung squamous cell carcinoma (SCC), which was histopathologically confirmed. The SCC metastasized to the nasopharynx following the bronchoscopy intervention therapies. The lesion was considered metastatic from lung cancer on the basis of clinical and histological clues. The exact mechanism of lung cancer metastasis to the nasopharynx in this case remains unclear because either implantation or hematogenous and lymphatic spread is possible. A thorough head and neck examination should be undertaken during bronchoscopic evaluation, especially in patients receiving bronchoscopy intervention therapies. The early detection of a silent nasopharyngeal metastasis is important to choosing from among the multiple treatment options available.
鼻咽癌转移极为罕见，文献报道的病例较少。在本报告中，我们描述了一名通过支气管镜检查发现鼻咽部有肿物的患者。我们的患者是一名61岁男性，因晚期肺鳞状细胞癌（SCC）接受了多次支气管镜介入治疗，病理组织学确诊为SCC。在支气管镜介入治疗后，SCC转移至鼻咽部。根据临床和组织学线索，该病变被认为是肺癌转移所致。由于种植转移、血行转移和淋巴转移均有可能，该病例中肺癌转移至鼻咽部的确切机制尚不清楚。在支气管镜评估过程中，尤其是对接受支气管镜介入治疗的患者，应进行全面的头颈部检查。早期发现无症状的鼻咽转移对于从多种可用治疗方案中进行选择非常重要。
