Saab G A, Abdul-Karim F W, Samara M
J Laryngol Otol. 1987 Jul;101(7):723-5. doi: 10.1017/s0022215100102609.
A case report of a patient with adenocarcinoma of the breast with metastasis to the nasopharynx is described. The patient presented initially with pulmonary metastasis followed later by metastasis to the left jugulo-digastric lymph nodes. A prominent but asymptomatic nasopharyngeal mass was concomitantly discovered on head and neck examination. Three months later, symptoms of panhypopituitarism developed. Invasion of the base of the skull and pituitary were documented. Patients with adenocarcinoma of the breast and high cervical node metastasis should have a thorough otolaryngologic and head and neck evaluation. Metastatic carcinoma to the nasopharynx is an extremely rare occurrence. Only two cases of bronchogenic carcinoma of the lung and two cases of hypernephroma metastatic to the nasopharynx have been reported in the literature (Bernstein et al., 1966). We present what we believe to be the first case of metastatic adenocarcinoma of the breast to the nasopharynx.
本文描述了一例乳腺癌转移至鼻咽部的病例报告。该患者最初出现肺转移，随后转移至左侧颈二腹肌下淋巴结。在头颈部检查中同时发现一个明显但无症状的鼻咽部肿物。三个月后，出现全垂体功能减退症状。记录显示有颅底和垂体侵犯。患有乳腺癌且有高位颈淋巴结转移的患者应进行全面的耳鼻喉科及头颈部评估。转移至鼻咽部的癌极为罕见。文献中仅报道过两例肺癌支气管源性癌和两例肾癌转移至鼻咽部的病例（伯恩斯坦等人，1966年）。我们呈现了我们认为是首例乳腺癌转移至鼻咽部的病例。
