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巨大主动脉综合征的混合多步骤方法:卢皮亚技术

Hybrid multistep approach to mega-aortic syndrome: the Lupiae technique.

作者信息

Esposito Giampiero, Pennesi Matteo, Bichi Samuele, Patrini Davide, Pellegrino Pasquale, Redaelli Marianna, Poloni Camillo, Gerometta Piersilvio, Gentinetta Franco, Cappabianca Giangiuseppe

机构信息

Cardiovascular Department, Humanitas Gavazzeni, Bergamo, Italy

Cardiovascular Department, Humanitas Gavazzeni, Bergamo, Italy.

出版信息

Eur J Cardiothorac Surg. 2015 Jan;47(1):126-33; discussion 133. doi: 10.1093/ejcts/ezu102. Epub 2014 Mar 27.

Abstract

OBJECTIVES

Several techniques have been described for the treatment of thoraco-abdominal aneurysms in patients with mega-aortic syndrome (MAS), but the incidence of stroke, spinal cord injury and endoleaks remains significant. We present the mid-term results of a new hybrid, multistep technique to treat patients with MAS.

METHODS

From November 2005 to November 2012, 118 patients with MAS underwent surgical repair of thoracic and thoraco-abdominal aneurysms with the Lupiae technique. Fifty-five patients presented chronic aneurysms and 63 patients Type A acute dissections. Eighty-three patients underwent ascending aorta and arch replacement with a multibranched Dacron graft and epiaortic vessels rerouting (thoracic Lupiae procedure). Twenty patients had the thoracic Lupiae procedure plus partial visceral debranching (coeliac trunk and superior mesenteric artery [SMA]) through an upper mini-laparotomy. Fifteen patients had the thoracic Lupiae procedure plus a complete visceral debranching (coeliac trunk, SMA and renal arteries) using a second multibranched Dacron graft to replace the infrarenal aorta. All the patients with chronic aneurysms and 34 of 63 patients with Type A dissections underwent implant of endovascular stent grafts.

RESULTS

In-hospital mortality was 8.4%. No patients had stroke or spinal cord injury. The incidence of temporary renal failure was 5.2%. No patients presented endoleaks immediately and at follow-up CT scans. No death or reoperation occurred during the follow-up.

CONCLUSIONS

These results evidence that the Lupiae technique is a safe and effective option for the treatment of patients with MAS, achieving the complete exclusion of thoraco-abdominal aneurysms and of the residual false lumen in patients with acute aortic dissections.

摘要

目的

已经描述了几种治疗巨主动脉综合征(MAS)患者胸腹主动脉瘤的技术,但中风、脊髓损伤和内漏的发生率仍然很高。我们展示了一种新型混合多步骤技术治疗MAS患者的中期结果。

方法

2005年11月至2012年11月,118例MAS患者采用Lupiae技术接受胸主动脉和胸腹主动脉瘤的手术修复。55例患者为慢性动脉瘤,63例患者为A型急性夹层。83例患者采用多分支涤纶移植物进行升主动脉和主动脉弓置换并重新路由主动脉外膜血管(胸段Lupiae手术)。20例患者通过上腹部小切口进行胸段Lupiae手术加部分内脏去分支(腹腔干和肠系膜上动脉[SMA])。15例患者采用胸段Lupiae手术加完全内脏去分支(腹腔干、SMA和肾动脉),使用第二个多分支涤纶移植物替换肾下腹主动脉。所有慢性动脉瘤患者和63例A型夹层患者中的34例接受了血管内支架移植物植入。

结果

住院死亡率为8.4%。没有患者发生中风或脊髓损伤。临时肾衰竭的发生率为5.2%。在随访CT扫描时,没有患者立即出现内漏。随访期间没有死亡或再次手术发生。

结论

这些结果证明Lupiae技术是治疗MAS患者的一种安全有效的选择,能够完全排除胸腹主动脉瘤以及急性主动脉夹层患者的残余假腔。

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