Tse R, Nixon J N, Iyer R S, Kuhlman-Wood K A, Ishak G E
the Division of Plastic Surgery, Department of Surgery (R.T., K.A.K.-W.), the Seattle Children's Hospital, University of Washington, Seattle, Washington.
From the Department of Radiology (J.N.N., R.S.L., G.E.I.).
AJNR Am J Neuroradiol. 2014 Jul;35(7):1425-32. doi: 10.3174/ajnr.A3878. Epub 2014 Mar 27.
Although most infants with brachial plexus palsy recover function spontaneously, approximately 10-30% benefit from surgical treatment. Pre-operative screening for nerve root avulsions is helpful in planning reconstruction. Our aim was to compare the diagnostic value of CT myelography, MR myelography, and both against a surgical criterion standard for detection of complete nerve root avulsions in birth brachial plexus palsy.
Nineteen patients who underwent a preoperative CT and/or MR myelography and subsequent brachial plexus exploration were included. Imaging studies were analyzed for the presence of abnormalities potentially predictive of nerve root avulsion. Findings of nerve root avulsion on surgical exploration were used as the criterion standard to assess the predictive value of imaging findings.
Ninety-five root levels were examined. When the presence of any pseudomeningocele was used as a predictor, the sensitivity was 0.73 for CT and 0.68 for MR imaging and the specificity was 0.96 for CT and 0.97 for MR imaging. When presence of pseudomeningocele with absent rootlets was used as the predictor, the sensitivity was 0.68 for CT and 0.68 for MR imaging and the specificity was 0.96 for CT and 0.97 for MR imaging. The use of both CT and MR imaging did not increase diagnostic accuracy. Rootlet findings in the absence of pseudomeningocele were not helpful in predicting complete nerve root avulsion.
Findings of CT and MR myelography were highly correlated. Given the advantages of MR myelography, it is now the single technique for preoperative evaluation of nerve root avulsion at our institution.
尽管大多数臂丛神经麻痹婴儿的功能可自发恢复,但约10%-30%的患儿可从手术治疗中获益。术前筛查神经根撕脱有助于规划重建手术。我们的目的是比较CT脊髓造影、MR脊髓造影以及两者联合应用相对于手术标准在诊断产伤性臂丛神经麻痹中完全神经根撕脱的诊断价值。
纳入19例术前行CT和/或MR脊髓造影并随后进行臂丛神经探查的患者。分析影像学检查结果,以确定是否存在可能提示神经根撕脱的异常表现。将手术探查中发现的神经根撕脱结果作为评估影像学检查结果预测价值的标准。
共检查了95个神经根节段。以任何假性脊膜膨出的存在作为预测指标时,CT的敏感性为0.73,MR成像的敏感性为0.68;CT的特异性为0.96,MR成像的特异性为0.97。以存在假性脊膜膨出且神经根缺失作为预测指标时,CT的敏感性为0.68,MR成像的敏感性为0.68;CT的特异性为0.96,MR成像的特异性为0.97。联合使用CT和MR成像并未提高诊断准确性。在无假性脊膜膨出情况下的神经根表现对预测完全神经根撕脱并无帮助。
CT和MR脊髓造影的结果高度相关。鉴于MR脊髓造影的优势,目前它是我们机构术前评估神经根撕脱的单一技术。