Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
JAMA Ophthalmol. 2014 May;132(5):633-6. doi: 10.1001/jamaophthalmol.2013.8243.
To report the clinical and histopathologic findings of ocular adnexal angiolymphoid hyperplasia with eosinophilia, an unusual but often misdiagnosed benign disorder.
The ophthalmologic findings of angiolymphoid hyperplasia with eosinophilia with ocular adnexal involvement are variable and include eyelid swelling, ptosis, proptosis, and loss of vision. Imaging studies typically reveal a well-circumscribed mass in the orbit. The condition may resemble other diseases that involve the orbit and ocular adnexal tissue, such as lymphoma, hemangioma, sarcoidosis, and dermoid cyst. Histopathologic analysis reveals marked vascular proliferation with an accompanying inflammation composed of numerous eosinophils, lymphocytes, and plasma cells.
Angiolymphoid hyperplasia with eosinophilia is a rare disease that can affect the ocular adnexal tissue. The clinical presentation is often nonspecific; therefore, histopathologic studies are essential for diagnosis and subsequent management of this benign condition.
报告眼部附属器血管淋巴样组织增生伴嗜酸性粒细胞增多症的临床和组织病理学表现，这是一种不常见但常被误诊的良性疾病。
眼部附属器血管淋巴样组织增生伴嗜酸性粒细胞增多症的眼部表现多种多样，包括眼睑肿胀、上睑下垂、眼球突出和视力丧失。影像学检查通常显示眼眶内界限清楚的肿块。该疾病可能类似于累及眼眶和眼部附属组织的其他疾病，如淋巴瘤、血管瘤、类肉瘤病和皮样囊肿。组织病理学分析显示明显的血管增生，伴有大量嗜酸性粒细胞、淋巴细胞和浆细胞的伴随炎症。
血管淋巴样组织增生伴嗜酸性粒细胞增多症是一种罕见的疾病，可影响眼部附属组织。临床表现通常是非特异性的；因此，组织病理学研究对于这种良性疾病的诊断和后续管理至关重要。
