Aguirre Anna Rita, Abensur Hugo
Faculdade de Medicina, Universidade de Sao Paulo.
J Bras Nefrol. 2014 Jan-Mar;36(1):74-9. doi: 10.5935/0101-2800.20140013.
In this review, phenomena involved in fluid and solute exchange through the peritoneal membrane, both in the physiologic and in the peritoneal dialysis settings, are explained. For that purpose, mathematical models developed for the study of molecule transport through the membrane, such as the "Pore Model" and the "Distributive Model" are used. Scientific accomplishments in the field are described and areas that require additional research are also cited. Knowledge about the physiologic mechanisms involved in this renal replacement therapy modality, concerning events directly related to the peritoneal membrane itself, is synthesized in this manuscript.
在本综述中，对生理状态及腹膜透析环境下通过腹膜进行的液体和溶质交换所涉及的现象进行了解释。为此，使用了为研究分子通过膜的转运而开发的数学模型，如“孔隙模型”和“分配模型”。描述了该领域的科学成就，并列举了需要进一步研究的领域。本文综合了关于这种肾脏替代治疗方式中涉及的生理机制的知识，这些知识涉及与腹膜本身直接相关的事件。
