Donno Dario, Beccaro Gabriele Loris, Mellano Maria Gabriella, Bonvegna Luca, Bounous Giancarlo
Dipartimento di Scienze Agrarie, Forestali e Alimentari, Università degli Studi di Torino, Via Leonardo da Vinci 44, 10095 -, Grugliasco (TO), Italy.
J Sci Food Agric. 2014 Nov;94(14):2863-73. doi: 10.1002/jsfa.6627. Epub 2014 Mar 24.
Many plant species may be used for the production of herbal preparations containing phytochemicals with significant antioxidant and anti-inflammatory capacities and health benefits: Castanea spp. is among the most commonly used herbal medicines. The aim of this research was to perform an analytical study of chestnut bud preparations, in order to identify and quantify the main bioactive compounds, and to obtain a specific chemical fingerprint to evaluate the single class contribution to the herbal preparation phytocomplex. The analyses were performed using a high-performance liquid chromatograph coupled to a diode array detector.
Castanea spp. was identified as a rich source of anti-inflammatory and antioxidant compounds: the observed analytical fingerprint demonstrated that these bud preparations represent a rich source of bioactive compounds (104.77 ± 1.14 g kg(-1) FW) in relation to different genotypes, specific sampling sites and several phenological stages.
This study showed that the observed analytical fingerprint can be considered an important tool for assessing the chemical composition and bioactivities of the chestnut-derived products, considering the Castanea genus as a new source of natural health-promoting compounds. This study allowed the development of an effective tool for quality control by fingerprinting the bud preparation in order to develop a new generation of standardised preparations.
许多植物物种可用于生产含有具有显著抗氧化和抗炎能力及健康益处的植物化学物质的草药制剂:栗属植物是最常用的草药之一。本研究的目的是对栗芽制剂进行分析研究,以鉴定和定量主要生物活性化合物,并获得特定的化学指纹图谱,以评估单一类别对草药制剂植物复合物的贡献。分析使用与二极管阵列检测器联用的高效液相色谱仪进行。
栗属植物被鉴定为富含抗炎和抗氧化化合物:观察到的分析指纹图谱表明,这些芽制剂相对于不同基因型、特定采样地点和几个物候阶段而言,是生物活性化合物的丰富来源(104.77±1.14 g kg(-1)鲜重)。
本研究表明,考虑到栗属作为天然健康促进化合物的新来源,观察到的分析指纹图谱可被视为评估栗属衍生产品的化学成分和生物活性的重要工具。本研究通过对芽制剂进行指纹图谱分析,开发了一种有效的质量控制工具,以开发新一代标准化制剂。