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多发性硬化症球后视神经炎后对比敏感度测量的评估

Evaluation of contrast sensitivity measurements after retrobulbar optic neuritis in Multiple Sclerosis.

作者信息

Owidzka Marta, Wilczynski Michal, Omulecki Wojciech

机构信息

Department of Ophthalmology, Medical University of Lodz, Medical University Barlicki Hospital No.1, Kopcinskiego str. 22, 90-153, Lodz, Poland,

出版信息

Graefes Arch Clin Exp Ophthalmol. 2014 Apr;252(4):673-7. doi: 10.1007/s00417-014-2590-x. Epub 2014 Feb 28.

Abstract

BACKGROUND

The evaluation of contrast sensitivity is an important additional examination that allows the physician to achieve the full picture of a patient's quality of vision. In low-contrast conditions, more discrete visual dysfunctions may be revealed, which could be overlooked in high-contrast tests.

METHODS

The examined group consisted of 33 eyes of 27 patients with multiple sclerosis. The study included patients with full or almost full visual acuity, without visual field defects or any other ophthalmic condition, and who had never undergone any ocular surgery or trauma. The reference group consisted of 49 eyes of 37 patients. This group included healthy subjects with full visual acuity. Contrast sensitivity was examined with a Functional Vision Analyzer™ device in photopic conditions (with and without glare) and in mesopic conditions (with and without glare).

RESULTS

In patients with multiple sclerosis who had experienced optic neuritis, contrast sensitivity was found to be significantly reduced in all spatial frequencies in both mesopic and photopic conditions (with and without glare).

CONCLUSIONS

Contrast sensitivity in patients with multiple sclerosis who have also had optic neuritis is significantly reduced. This may explain patients' complaints regarding their quality of vision, despite good visual acuity. Contrastometry is a useful basis for further examination, providing additional information regarding a patient's quality of vision.

摘要

背景

对比敏感度评估是一项重要的补充检查,可使医生全面了解患者的视觉质量。在低对比度条件下,可能会发现更多细微的视觉功能障碍,而这些在高对比度测试中可能会被忽略。

方法

受检组由27例多发性硬化症患者的33只眼睛组成。该研究纳入了视力完全或几乎完全正常、无视野缺损或任何其他眼科疾病、且从未接受过任何眼部手术或外伤的患者。参照组由37例患者的49只眼睛组成。该组包括视力正常的健康受试者。使用功能性视觉分析仪™设备在明视条件下(有和没有眩光)以及在 mesopic 条件下(有和没有眩光)检查对比敏感度。

结果

在患有视神经炎的多发性硬化症患者中,发现在 mesopic 和明视条件下(有和没有眩光)所有空间频率的对比敏感度均显著降低。

结论

患有视神经炎的多发性硬化症患者的对比敏感度显著降低。这可能解释了尽管视力良好,但患者仍抱怨其视觉质量的原因。对比测量法是进一步检查的有用基础,可提供有关患者视觉质量的额外信息。

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