Gotoda Takuji, Ho Khek-Yu, Soetikno Roy, Kaltenbach Tonya, Draganov Peter
Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Level 10, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228.
Gastrointest Endosc Clin N Am. 2014 Apr;24(2):213-33. doi: 10.1016/j.giec.2013.11.009. Epub 2014 Jan 28.
Endoscopic mucosal resection (EMR) of early gastric cancer, which has been proved to be safe and effective and is the established standard of care in Japan, has become increasingly established worldwide in the past decade. Endoscopic submucosal dissection (ESD) is superior to EMR, as it is designed to provide precise pathologic staging and long-term curative therapy based on an en bloc R0 specimen irrespective of the size and/or location of the tumor. However, ESD requires highly skilled and experienced endoscopists. The introduction of ESD to the Western world necessitates collaborations between Eastern and Western endoscopists, pathologists, and surgeons.
早期胃癌的内镜黏膜切除术(EMR)已被证明是安全有效的,并且在日本是既定的治疗标准,在过去十年中已在全球范围内越来越多地确立。内镜黏膜下剥离术(ESD)优于EMR,因为它旨在基于整块R0标本提供精确的病理分期和长期治愈性治疗,而不论肿瘤的大小和/或位置如何。然而,ESD需要技术高超且经验丰富的内镜医师。将ESD引入西方世界需要东西方的内镜医师、病理学家和外科医生之间的合作。