Lankarani Kamran B, Ravanbod Mohammad Reza, Aflaki Elham, Nazarinia Mohammad Ali, Rajaee Akbar
Health policy Research Center, Shiraz University of Medical Sciences, P,O, Box 71345-1414, Shiraz, Islamic Republic of Iran.
BMC Gastroenterol. 2014 Mar 31;14:58. doi: 10.1186/1471-230X-14-58.
Behcet's disease (BD) is a multisystem disease of unknown etiology. There are several clues which may indicate an ethiopathogenesis role for Helicobacter pylori infection in this disease.
In a case control study in an out patient department, 48 patients with BD were compared to age, sex matched controls regarding presence of H. pylori infection by serology and urea breath test (UBT).
Ongoing H. pylori infection was more prevalent among patients with BD using result of UBT with odds ratio of 3.1 (95% CI: 1.34 - 7.26, PV < 0.001).
H. pylori infection may have a role in the pathogenesis of BD.
白塞病(BD)是一种病因不明的多系统疾病。有几条线索表明幽门螺杆菌感染在该疾病的病因发病机制中可能起作用。
在一个门诊部进行的病例对照研究中,通过血清学和尿素呼气试验(UBT),将48例白塞病患者与年龄、性别匹配的对照组就幽门螺杆菌感染情况进行比较。
根据尿素呼气试验结果,正在进行的幽门螺杆菌感染在白塞病患者中更为普遍,优势比为3.1(95%置信区间:1.34 - 7.26,P值<0.001)。
幽门螺杆菌感染可能在白塞病的发病机制中起作用。