Kimura H, Odani S, Suzuki J, Arakawa M, Ono T
Department of Biochemistry, Niigata University School of Medicine, Japan.
FEBS Lett. 1989 Mar 27;246(1-2):101-4. doi: 10.1016/0014-5793(89)80261-3.
A fatty acid-binding protein was purified from male rat kidney by the method of Fujii et al. [(1987) Arch. Biochem. Biophys. 254, 552-558]. Based on the close similarity of amino acid composition and the identity of the amino acid sequence in the amino-terminal region, the fatty acid-binding protein was identified as alpha 2U-globulin, which is the major male-specific protein in rat urine. The amino-terminal residue of the isolated kidney protein corresponds to residue 10 of alpha 2U-globulin, suggesting that the protein has been proteolytically processed in the kidney. This fatty acid-binding protein could not be immunologically detected in female rat kidney.
