Catterick David, Hunt Beverly J
aDepartment of Economics, City University London, London bHealth Outcomes Department, Sanofi, Guildford, Surrey cKing's College, London and Guy's and St Thomas' NHS Foundation Trust, London, UK.
Blood Coagul Fibrinolysis. 2014 Sep;25(6):571-6. doi: 10.1097/MBC.0000000000000100.
Venous thromboembolism (VTE) is a common and important cause of death in hospital patients. We therefore investigated possible associations between the introduction of the compulsory national VTE risk assessment tool in England in 2010 and patient outcomes. A retrospective database study, using data from the Health and Social Care Information Centre and Office of National Statistics, was undertaken. The main outcome measures were VTE-related secondary diagnosis rates, 30-day and 90-day readmission rates and mortality rates. The observed mean VTE-related secondary diagnosis rate for 2011-2012 was 91% of the rate estimated from a linear regression model of the data for 2006-2007 to 2010-2011 (P = 0.001). Similarly, the observed mean 30-day VTE-related readmission rate for 2011 was 96% of the estimated rate (P = 0.067) and the observed mean 90-day VTE-related readmission rate for 2011 was 96% of the estimated rate (P = 0.022). The observed annual VTE-related national mortality rate was 91% of the estimated rate for 2011 and 92% of the estimated rate for 2012. This study shows a reduction in VTE-related secondary diagnoses and readmissions among adults admitted to hospital, and a reduction in VTE-related population mortality, since the introduction of a national VTE risk assessment screening tool in England. Despite some study limitations, this suggests that the concerted effort made by NHS England to improve prevention of hospital-acquired VTE has been successful.
静脉血栓栓塞症(VTE)是住院患者常见且重要的死亡原因。因此,我们调查了2010年英格兰强制推行全国VTE风险评估工具与患者预后之间可能存在的关联。我们利用来自健康与社会保健信息中心及国家统计局的数据进行了一项回顾性数据库研究。主要结局指标为VTE相关的二次诊断率、30天和90天再入院率以及死亡率。2011 - 2012年观察到的VTE相关二次诊断率均值为根据2006 - 2007年至2010 - 2011年数据的线性回归模型估算率的91%(P = 0.001)。同样,2011年观察到的30天VTE相关再入院率均值为估算率的96%(P = 0.067),2011年观察到的90天VTE相关再入院率均值为估算率的96%(P = 0.022)。2011年观察到的全国VTE相关年度死亡率为估算率的91%,2012年为估算率的92%。这项研究表明,自英格兰引入全国VTE风险评估筛查工具以来,住院成人中VTE相关的二次诊断和再入院情况有所减少,VTE相关的总体死亡率也有所降低。尽管该研究存在一些局限性,但这表明英格兰国民保健服务体系为改善医院获得性VTE预防所做的协同努力取得了成功。