Wang Ruoya, Gleason Rudolph L
J Biomech Eng. 2014 Jun;136(6):061004. doi: 10.1115/1.4027331.
Quantifying arterial residual deformations is critical for understanding the stresses and strains within the arterial wall during physiological and pathophysiological conditions. This study presents novel findings on residual shear deformations in the left anterior descending coronary artery. Residual shear deformations are most evident when thin, long axial strips are cut from the artery. These strips deform into helical configurations when placed in isotonic solution. A residual shear angle is introduced as a parameter to quantify the residual shear deformations. Furthermore, a stress analysis is performed to study the effects of residual shear deformations on the intramural shear stress distribution of an artery subjected to pressure, axial stretch, and torsion using numerical simulation. The results from the stress analyses suggest that residual shear deformations can significantly modulate the intramural shear stress across the arterial wall.
量化动脉残余变形对于理解生理和病理生理条件下动脉壁内的应力和应变至关重要。本研究提出了关于左前降支冠状动脉残余剪切变形的新发现。当从动脉中切下细而长的轴向条带时，残余剪切变形最为明显。将这些条带置于等渗溶液中时，它们会变形为螺旋状结构。引入残余剪切角作为量化残余剪切变形的参数。此外，进行了应力分析，以使用数值模拟研究残余剪切变形对承受压力、轴向拉伸和扭转的动脉壁内剪切应力分布的影响。应力分析结果表明，残余剪切变形可显著调节整个动脉壁内的剪切应力。
