Moe-Behrens Gerd Hg
Leukippos Institute, Berlin, Germany.
Comput Struct Biotechnol J. 2013 Jun 26;7:e201304003. doi: 10.5936/csbj.201304003. eCollection 2013.
Systemics, a revolutionary paradigm shift in scientific thinking, with applications in systems biology, and synthetic biology, have led to the idea of using silicon computers and their engineering principles as a blueprint for the engineering of a similar machine made from biological parts. Here we describe these building blocks and how they can be assembled to a general purpose computer system, a biological microprocessor. Such a system consists of biological parts building an input / output device, an arithmetic logic unit, a control unit, memory, and wires (busses) to interconnect these components. A biocomputer can be used to monitor and control a biological system.
系统学是科学思维中一场革命性的范式转变,在系统生物学和合成生物学中有着应用,它催生了将硅计算机及其工程原理作为由生物部件制成的类似机器工程蓝图的想法。在此,我们描述这些构建模块以及它们如何组装成一个通用计算机系统——生物微处理器。这样一个系统由构建输入/输出设备、算术逻辑单元、控制单元、存储器以及用于互连这些组件的线路(总线)的生物部件组成。生物计算机可用于监测和控制生物系统。