Safronova T I, Ivanova S B, Lyzlova S N
Zh Evol Biokhim Fiziol. 1988 Nov-Dec;24(6):835-41.
Studies have been made on interaction between rabbit antiserum to BB creatine kinase from hen gizzard and BB creatine kinases from the brain, heart and gizzard of hen. The degree of interaction was evaluated by the intensity of fluorescence of the immune complexes labeled by a fluorescent dye. It was shown that the intensity of fluorescence of the immune complexes formed by BB creatine kinases from the brain and gizzard of hen is approximately the same, whereas that formed by BB creatine kinase from the heart is twice lower. The data obtained indicate that structural differences in the region of antigenic determinants exist between BB creatine kinase from the heart and those from the brain and gizzard of hen.
已经对兔抗鸡砂囊BB型肌酸激酶抗血清与鸡脑、心脏和砂囊的BB型肌酸激酶之间的相互作用进行了研究。通过荧光染料标记的免疫复合物的荧光强度来评估相互作用的程度。结果表明，鸡脑和砂囊的BB型肌酸激酶形成的免疫复合物的荧光强度大致相同，而心脏的BB型肌酸激酶形成的免疫复合物的荧光强度则低两倍。所获得的数据表明，鸡心脏的BB型肌酸激酶与鸡脑和砂囊的BB型肌酸激酶在抗原决定簇区域存在结构差异。
