Pieńkowska D, Kunikowska D, Głośnicka R
Bull Inst Marit Trop Med Gdynia. 1993;44-45(1-4):89-93.
As a result of fusion of in vitro immunized mouse splenocytes and myeloma Sp2/0 cells, stable hybridomas secreting monoclonal antibodies against Vi antigen were obtained. The monoclonal antibodies were of IgM class. Reactivity of monoclonal antibodies to Vi antigen of different origin was tested. The reactivity was found to be independent of O-acetylation degree of Vi antigen.
通过体外免疫小鼠脾细胞与骨髓瘤Sp2/0细胞融合，获得了分泌抗Vi抗原单克隆抗体的稳定杂交瘤。这些单克隆抗体属于IgM类。检测了单克隆抗体对不同来源Vi抗原的反应性。发现该反应性与Vi抗原的O-乙酰化程度无关。
