一种来自乌桕（大戟科）的新型三萜类化合物。

A new triterpenoid from Sapium baccatum (Euphorbiaceae).

作者信息

Al Muqarrabun L M Ramadhan, Ahmat Norizan, Aris S Ruzaina S, Norizan Norhazana, Shamsulrijal Nurdiana, Yusof Farida Z M, Suratman M Nazip, Yusof M Izwan M, Salim Fatimah

机构信息

a Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM) , 40450 Shah Alam , Selangor , Malaysia.

出版信息

Nat Prod Res. 2014;28(13):1003-9. doi: 10.1080/14786419.2014.903396. Epub 2014 Apr 4.

DOI:10.1080/14786419.2014.903396

PMID:24697194

Abstract

A new triterpene, malaytaraxerate (1), and four known compounds, taraxerol (2), taraxerone (3), docosyl isoferulate (4) and docosanoic acid 2',3'-dihydroxypropyl ester (5), were isolated from the acetone extract of Sapium baccatum stem bark. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-Vis, FT-IR, 1D and 2D NMR, and mass spectrometry. Major isolated compounds were assayed for cytotoxicity. The chemotaxonomic significance of this plant was also studied.

摘要

从重阳木茎皮的丙酮提取物中分离出一种新的三萜类化合物——马来蒲公英甾醇（1），以及四种已知化合物——蒲公英赛醇（2）、蒲公英赛酮（3）、二十二烷基异阿魏酸酯（4）和二十二烷酸2',3'-二羟基丙酯（5）。采用紫外可见光谱、傅里叶变换红外光谱、一维和二维核磁共振以及质谱等多种光谱方法确定了分离出的化合物的结构。对主要分离出的化合物进行了细胞毒性测定。还研究了该植物的化学分类学意义。