Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan; Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
J Am Geriatr Soc. 2014 Apr;62(4):706-10. doi: 10.1111/jgs.12736. Epub 2014 Apr 2.
To describe trends in advance directive (AD) completion from 2000 to 2010 and to explore the relationship between AD and hospitalization and hospital death at the end of life.
Retrospective cohort study.
Health and Retirement Study (HRS).
HRS participants who died between 2000 and 2010 and were aged 60 and older at death (N = 6,122).
Trends over time in rates of AD completion, hospitalization before death, and death in hospital are described. The association between trends in AD completion and hospital death was then assessed by comparing nested, multivariable logistic regression models predicting the odds of hospital death over time with and without adjusting for AD status and sociodemographic characteristics. The complex sampling design was accounted for in all analyses.
The proportion of decedents with an AD increased from 47% in 2000 to 72% in 2010. At the same time, the proportion of decedents with at least one hospitalization in the last 2 years of life increased from 52% to 71%, and the proportion dying in the hospital decreased from 45% to 35%. After adjusting for confounding by sociodemographic characteristics, the trend in declining hospital death over the decade was negligibly associated with the greater use of ADs.
There has been a significant increase in rates of AD completion over the last decade, but this trend has had little effect upon hospitalization and hospital death, suggesting that AD completion is unlikely to stem hospitalization before death.
描述 2000 年至 2010 年期间预立医疗指示(AD)完成情况的趋势,并探讨 AD 与临终时住院和医院死亡之间的关系。
回顾性队列研究。
健康与退休研究(HRS)。
HRS 参与者在 2000 年至 2010 年期间死亡,死亡时年龄在 60 岁及以上(N=6122)。
描述 AD 完成率、死前住院和医院死亡的时间趋势。然后,通过比较嵌套的多变量逻辑回归模型来评估 AD 完成趋势与医院死亡之间的关联,该模型预测随时间推移的医院死亡几率,调整和不调整 AD 状态和社会人口学特征。所有分析均考虑了复杂的抽样设计。
有 AD 的死者比例从 2000 年的 47%增加到 2010 年的 72%。与此同时,在生命的最后 2 年至少有一次住院的死者比例从 52%增加到 71%,而在医院死亡的比例从 45%下降到 35%。在调整社会人口学特征混杂因素后,在过去十年中,医院死亡的下降趋势与 AD 使用量的增加几乎没有关联。
在过去十年中,AD 完成率显著增加,但这一趋势对住院和医院死亡几乎没有影响,这表明 AD 完成不太可能阻止死亡前的住院。