Zurochka A V, Dolgushin I I, Vlasov A V, Riabinin V E
Lab Delo. 1989(3):32-6.
The effects of various polystyrene monodispersed latexes on neutrophil chemiluminescence (CL) induction have been studied. The studies have revealed that latexes may be employed as neutrophil CL activators. Latexes with a diameter of 1.7 micron could induce CL of the highest intensity. An increase or decrease in the diameter of latex particles reduced the intensity of neutrophil CL induction. Gamma-globulin or immunoglobulin coating of latex lowered, whereas zinc methacrylate coating enhanced the intensity of the reaction. Since latexes induce a maximum respiratory outburst in the first two minutes after their introduction in cellular suspension, they may be referred to as rapid inductors of neutrophil CL.
研究了各种聚苯乙烯单分散乳胶对中性粒细胞化学发光(CL)诱导的影响。研究表明,乳胶可用作中性粒细胞CL激活剂。直径为1.7微米的乳胶可诱导最高强度的CL。乳胶颗粒直径的增加或减小会降低中性粒细胞CL诱导的强度。乳胶的γ-球蛋白或免疫球蛋白包被会降低反应强度,而甲基丙烯酸锌包被则会增强反应强度。由于乳胶在引入细胞悬液后的前两分钟内诱导最大呼吸爆发,它们可被称为中性粒细胞CL的快速诱导剂。