Department of Dermatology, San Gallicano Institute IRCCS, Rome, Italy.
Dermatol Surg. 2014 May;40(5):553-61. doi: 10.1111/dsu.12470. Epub 2014 Apr 3.
The therapeutic approach to the treatment of acne scars and photoaging varies according to the type of lesion. Traditional carbon dioxide (CO2 ) laser is associated with long healing times, persistent erythema, and high risk of post-inflammatory hyperpigmentation. Fractional laser technology, which involves the application of microscopic beams of pixilated light inducing focal zones of tissue injury surrounded by normal tissue, is currently used for the treatment of acne scars and photoaging.
To compare the results obtained using CO2 fractional laser with those obtained using CO2 fractional laser plus radiofrequency for the treatment of atrophic acne scars and photoaging by means of clinical evaluation and confocal laser.
Ten patients with photoaging and acne scars underwent a single treatment using both technologies. Investigators and patients evaluated the clinical effect of the treatments using digital photographs, dermatoscopy, and in vivo reflectance confocal microscopy before and immediately, 1 week, and 3 months after treatment.
Our results underlined the high efficacy of combining CO2 laser and radiofrequency, producing better results with fewer sessions, lower risks, and fewer side effects.
痤疮瘢痕和光老化的治疗方法因病变类型而异。传统的二氧化碳（CO2）激光治疗后愈合时间长，持续红斑，炎症后色素沉着风险高。目前，应用微光束分割成像素状的光，诱导正常组织周围的局灶性组织损伤的分束激光技术，用于治疗痤疮瘢痕和光老化。
通过临床评估和共聚焦激光比较 CO2 分束激光与 CO2 分束激光联合射频治疗萎缩性痤疮瘢痕和光老化的效果。
10 例光老化和痤疮瘢痕患者分别采用这两种技术进行单次治疗。治疗前后即刻、1 周和 3 个月，通过数码照片、皮肤镜和体内反射共聚焦显微镜，由观察者和患者评估治疗的临床效果。
结果表明 CO2 激光联合射频的疗效较高，疗程更少，风险更低，副作用更少。
