不同能量密度的点阵二氧化碳激光治疗亚洲人痤疮瘢痕的对比研究：一项随机对照自身左右脸试验。
Comparison study of fractional carbon dioxide laser resurfacing using different fluences and densities for acne scars in Asians: a randomized split-face trial.
机构信息
Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China; Department of Dermatology and Venereology, Yanbian University Hospital, Yanji, China.
出版信息
Dermatol Surg. 2014 May;40(5):545-52. doi: 10.1111/dsu.12467. Epub 2014 Mar 20.
BACKGROUND
Ablative 10,600-nm carbon dioxide (CO2 ) fractional laser treatments have shown favorable outcomes for atrophic acne scars.
OBJECTIVE
To compare the efficacy and complications of fractional CO2 laser treatments with different fluences and densities for acne scars.
METHODS
Twenty patients were treated using a single session of fractional CO2 laser in Deep FX mode. In Group A (n = 10), half of the face was treated with 20 mJ, density 10% and the other half with 20 mJ, density 20%. In Group B (n = 10), half of the face was treated with 10 mJ, density 10% and the other half with 20 mJ, density 10%. Patients were evaluated at baseline and 3 days, 1 week, 1 month, and 3 months after the procedure.
RESULTS
There was no significant difference in efficacy between different laser settings within the groups, although adverse effects were more evident in patients treated with higher densities or fluences.
CONCLUSION
Factional CO2 laser treatment using the Deep FX mode may provide a significant efficacy with lower fluence and density with fewer complications than with higher energies for acne scars.
背景
消融 10600nm 二氧化碳（CO2）点阵激光治疗对于萎缩性痤疮瘢痕显示出良好的疗效。
目的
比较不同能量密度的 CO2点阵激光治疗痤疮瘢痕的疗效和并发症。
方法
20 例患者采用 Deep FX 模式的单次 CO2 点阵激光治疗。在 A 组（n=10）中，一半的面部用 20mJ、密度 10%治疗，另一半用 20mJ、密度 20%治疗。在 B 组（n=10）中，一半的面部用 10mJ、密度 10%治疗，另一半用 20mJ、密度 10%治疗。患者在基线、术后 3 天、1 周、1 个月和 3 个月时进行评估。
结果
虽然在高能量密度或能量密度下，不良反应更为明显，但组内不同激光设置之间的疗效无显著差异。
结论
Deep FX 模式的 CO2 点阵激光治疗对于痤疮瘢痕，使用较低能量密度可提供显著疗效，且并发症少于高能量密度治疗。
Zotero 插件