Department of Dermatology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Dermatol Ther. 2019 Nov;32(6):e13084. doi: 10.1111/dth.13084. Epub 2019 Oct 7.
Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. To obtain satisfactory results for patients with scars, repetitive fractional laser therapy is always required; however, this treatment could easily lead to complications such as erythema, edema, infection, and post-inflammatory hyperpigmentation. In addition, different types of acne scars may have different responses to laser, further limiting its widespread use. In recent studies both home and abroad, a new pattern of fractional laser combined with other therapies to improve acne scar has been recommended to guarantee the safety and effective of treatment. This article reviews the recent pertinent literatures and summarized the progression of ablative fractional CO laser combined with other therapies on acne scar.
剥脱性二氧化碳点阵激光换肤术是治疗痤疮瘢痕的一线方法。其依据的是点阵式光热分解作用原理，通过制造多个微小的治疗区，来加速胶原形成和上皮再形成的愈合过程。目前，波长为 10600nm 的剥脱性 CO2 激光已广泛应用于美容和临床治疗各种皮肤病领域，可有效改善皮肤再生和瘢痕形成。为了使瘢痕患者获得满意的疗效，通常需要重复进行点阵激光治疗；但这种治疗容易引起红斑、水肿、感染和炎症后色素沉着过度等并发症。此外，不同类型的痤疮瘢痕对激光的反应可能不同，进一步限制了其广泛应用。近年来国内外研究推荐了一种新的模式，即联合其他疗法的点阵激光治疗以改善痤疮瘢痕，以保证治疗的安全性和有效性。本文复习了相关文献，综述了剥脱性 CO2 点阵激光联合其他疗法治疗痤疮瘢痕的研究进展。
