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疑似急性阑尾炎手术的全国前瞻性结局审核。

Prospective nationwide outcome audit of surgery for suspected acute appendicitis.

机构信息

Departments of Surgery, Tergooi Hospital, Hilversum, The Netherlands.

Academic Medical Centre, Amsterdam, The Netherlands.

出版信息

Br J Surg. 2016 Jan;103(1):144-51. doi: 10.1002/bjs.9964. Epub 2015 Oct 28.

Abstract

BACKGROUND

Studies comparing laparoscopic and open appendicectomy are difficult to interpret owing to several types of bias, and the results often seem of limited clinical importance. National audits can be valuable to provide insight into outcomes following appendicectomy at a population level.

METHODS

A prospective, observational, resident-led, nationwide audit was carried out over a period of 2 months, including all consecutive adult patients who had surgery for suspected acute appendicitis. Complications after laparoscopic and open appendicectomy were compared by means of logistic regression analysis; subgroup analyses were performed for patients with complicated appendicitis.

RESULTS

A total of 1975 patients were included from 62 participating Dutch hospitals. A normal appendix was seen in 3·3 per cent of patients. Appendicectomy was performed for acute appendicitis in 1378 patients, who were analysed. All but three patients underwent preoperative imaging. Laparoscopy was used in 79·5 per cent of patients; the conversion rate was 3·4 per cent. A histologically normal appendix was found in 2·2 per cent. Superficial surgical-site infection was less common in the laparoscopic group (odds ratio 0·25, 95 per cent c.i. 0·14 to 0·44; P < 0·001). The rate of intra-abdominal abscess formation was not significantly different following laparoscopic or open surgery (odds ratio 1·71, 0·80 to 3·63; P = 0·166). Similar findings were observed in patients with complicated appendicitis.

CONCLUSION

Management of acute appendicitis in the Netherlands is preferably performed laparoscopically, characterized by a low conversion rate. Fewer superficial surgical-site infections occurred with laparoscopy, although the rate of abscess formation was no different from that following open surgery. A low normal appendix rate is the presumed effect of a mandatory preoperative imaging strategy.

摘要

背景

由于存在多种类型的偏倚,腹腔镜与开腹阑尾切除术的比较研究难以解读,而且结果似乎通常具有有限的临床意义。全国性审计可以为了解人群水平阑尾切除术后的结果提供有价值的见解。

方法

在 2 个月的时间内进行了一项前瞻性、观察性、住院医师主导的全国性审计,包括所有接受疑似急性阑尾炎手术的连续成年患者。通过逻辑回归分析比较腹腔镜和开腹阑尾切除术的并发症;对复杂性阑尾炎患者进行了亚组分析。

结果

从 62 家荷兰参与医院共纳入 1975 名患者。3.3%的患者阑尾正常。对 1378 名患有急性阑尾炎的患者进行了阑尾切除术分析。除了三名患者外,所有患者均进行了术前影像学检查。79.5%的患者采用腹腔镜手术;转化率为 3.4%。2.2%的患者阑尾组织学正常。腹腔镜组浅表手术部位感染较少(优势比 0.25,95%置信区间 0.14 至 0.44;P<0.001)。腹腔镜或开腹手术后腹腔脓肿形成的发生率无显著差异(优势比 1.71,0.80 至 3.63;P=0.166)。在复杂性阑尾炎患者中也观察到了类似的发现。

结论

荷兰急性阑尾炎的治疗优选腹腔镜,其特点是转化率低。与开腹手术相比,腹腔镜手术发生浅表手术部位感染的几率较低,尽管脓肿形成的发生率与开腹手术无差异。正常阑尾的低发生率可能是术前影像学策略的强制实施所导致的。

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