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尼日利亚西北部索科托终末期肾病患者的血液透析性能及结果

Hemodialysis performance and outcomes among end stage renal disease patients from Sokoto, North-Western Nigeria.

作者信息

Makusidi M A, Liman H M, Yakubu A, Isah M D, Abdullahi S, Chijioke A

机构信息

Department of Medicine, Usmanu Danfodiyo, University Teaching Hospital, Sokoto, Nigeria.

Department of Nursing, Usmanu Danfodiyo, University Teaching Hospital, Sokoto, Nigeria.

出版信息

Indian J Nephrol. 2014 Mar;24(2):82-5. doi: 10.4103/0971-4065.127889.

Abstract

The cost of managing end stage renal disease (ESRD) is prohibitive in Nigeria and the burden is solely borne by patients and their relatives. Despite increasing number of dialysis centers in urban areas, actual utilization of such facilities is very low. It is unclear if the outcomes of these patients have improved in recent times. We evaluated pattern of hemodialysis (HD) performance and outcome among ESRD patients. A 5-year prospective cross-sectional study of all ESRD patients on HD was undertaken. The final outcomes included duration on maintenance dialysis, death from inability to sustain dialysis, absconded, confirmed deaths within or outside health facility or referral for kidney transplant. A total of 540 (54%) of 976 cases of ESRD commenced HD, out of which 7 (1.3%) eventually had live-related kidney transplant in India. The male to female ratio was 2:1 with male and female mean ages of 43 ± 17 and 36 ± 16 years respectively. There was a progressive annual increase in the number of ESRD patients. The commonest underlying renal disorder was chronic glomerulonephritis. The mean HD session duration was 8.11 ± 5.4 hours, while the mean duration of stay on HD was 8.72 ± 1.0 weeks. In conclusion, ESRD is common and is being increasingly recognized. Financial constraint and late presentation are major contributory factors to poor outcomes despite the widespread availability of HD facilities. Therefore, effort should be geared towards aggressive strategies for early detection and treatment. Government commitment in terms of funding and/or subsidy for patient with ESRD is advocated.

摘要

在尼日利亚,终末期肾病(ESRD)的治疗费用高得令人望而却步,负担完全由患者及其亲属承担。尽管城市地区的透析中心数量不断增加,但此类设施的实际利用率却非常低。目前尚不清楚这些患者的治疗效果近期是否有所改善。我们评估了ESRD患者的血液透析(HD)治疗模式和治疗效果。对所有接受HD治疗的ESRD患者进行了一项为期5年的前瞻性横断面研究。最终结果包括维持性透析的持续时间、因无法维持透析而死亡、潜逃、在医疗机构内或外确认的死亡或转介进行肾移植。976例ESRD病例中,共有540例(54%)开始接受HD治疗,其中7例(1.3%)最终在印度接受了活体亲属肾移植。男女比例为2:1,男性和女性的平均年龄分别为43±17岁和36±16岁。ESRD患者的数量逐年递增。最常见的潜在肾脏疾病是慢性肾小球肾炎。平均HD治疗疗程持续时间为8.11±5.4小时,而HD治疗的平均住院时间为8.72±1.0周。总之,ESRD很常见,并且越来越受到重视。尽管HD设施广泛可用,但经济限制和就诊延迟是导致治疗效果不佳的主要因素。因此,应致力于采取积极策略进行早期检测和治疗。提倡政府在为ESRD患者提供资金和/或补贴方面做出承诺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6824/3968614/cd56ea56ca96/IJN-24-82-g002.jpg

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