Environmental Biology Unit, Department of Pure and Applied Biology, Ladoke Akintola University of Technology, PMB 4000, Ogbomoso, Oyo State, Nigeria.
Evid Based Complement Alternat Med. 2014;2014:751291. doi: 10.1155/2014/751291. Epub 2014 Feb 20.
The safety of many African traditional herbal remedies is doubtful due to lack of standardization. This study therefore attempted to standardize two polyherbal formulations from Ogbomoso, Oyo State, Nigeria, with respect to the relative proportions (weight-for-weight) of their botanical constituents. Information supplied by 41 local herbal practitioners was statistically screened for consistency and then used to quantify the composition of antimalarial (Maloff-HB) and haematinic (Haematol-B) powdered herbal formulations with nine and ten herbs, respectively. Maloff-HB contained the stem bark of Enantia chlorantha Oliv. (30.0), Alstonia boonei De Wild (20.0), Mangifera indica L. (10.0), Okoubaka aubrevillei Phelleg & Nomand (8.0), Pterocarpus osun Craib (4.0), root bark of Calliandra haematocephala Hassk (10.0), Sarcocephalus latifolius (J. E. Smith) E. A. Bruce (8.0), Parquetina nigrescens (Afz.) Bullock (6.0), and the vines of Cassytha filiformis L. (4.0), while Haematol-B was composed of the leaf sheath of Sorghum bicolor Moench (30.0), fruit calyx of Hibiscus sabdariffa L. (20.0), stem bark of Theobroma cacao L. (10.0), Khaya senegalensis (Desr.) A. Juss (5.5), Mangifera indica (5.5), root of Aristolochia ringens Vahl. (7.0), root bark of Sarcocephalus latifolius (5.5), Uvaria chamae P. Beauv. (5.5), Zanthoxylum zanthoxyloides (Lam.) Zepern & Timler (5.5), and seed of Garcinia kola Heckel (5.5). In pursuance of their general acceptability, the two herbal formulations are recommended for their pharmaceutical, phytochemical, and microbial qualities.
由于缺乏标准化,许多非洲传统草药的安全性令人怀疑。因此,本研究试图对来自尼日利亚奥约州奥格博莫索的两种复方草药制剂进行标准化,以确定其植物成分的相对比例(重量比)。通过对 41 位当地草药医生提供的信息进行统计筛选,以确保其一致性,然后使用这些信息来定量确定抗疟(Maloff-HB)和补血(Haematol-B)两种粉状草药制剂的成分,这两种制剂分别含有 9 种和 10 种草药。Maloff-HB 含有恩坦西亚·克洛恩塔奥利夫(Enantia chlorantha Oliv.)的茎皮(30.0)、阿尔斯顿尼亚·布恩迪(Alstonia boonei De Wild)(20.0)、芒果(Mangifera indica L.)(10.0)、奥库巴卡·奥布雷维尔(Okoubaka aubrevillei Phelleg & Nomand)(8.0)、紫檀(Pterocarpus osun Craib)(4.0)、卡利安德拉·海玛托切法尔(Calliandra haematocephala Hassk)的根皮(10.0)、宽叶塞卡弗拉乌斯(Sarcocephalus latifolius)(8.0)、帕奎蒂娜·尼格雷塞斯(Parquetina nigrescens)(Afz.)布洛克(6.0)和卡西萨·菲尔弗里姆斯(Cassytha filiformis L.)的藤(4.0),而 Haematol-B 则由高粱(Sorghum bicolor Moench)的叶鞘(30.0)、芙蓉花(Hibiscus sabdariffa L.)的果萼(20.0)、可可树(Theobroma cacao L.)的茎皮(10.0)、塞内加尔黄檀(Khaya senegalensis(Desr.)A. Juss)(5.5)、芒果(Mangifera indica)(5.5)、阿斯特罗洛伊奇·林根斯(Aristolochia ringens Vahl.)的根(7.0)、宽叶塞卡弗拉乌斯(Sarcocephalus latifolius)的根皮(5.5)、乌瓦里·查梅(Uvaria chamae P. Beauv.)(5.5)、黄樟(Zanthoxylum zanthoxyloides(Lam.)Zepern & Timler)(5.5)和可乐果(Garcinia kola Heckel)的种子(5.5)。为了追求它们的普遍可接受性,建议将这两种草药制剂用于其药物、植物化学和微生物质量。