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尼日利亚西南部翁多州奥凯格博用于疟疾治疗的药用植物。

Medicinal plants useful for malaria therapy in Okeigbo, Ondo State, Southwest Nigeria.

作者信息

Odugbemi Tolu O, Akinsulire Odunayo R, Aibinu Ibukun E, Fabeku Peter O

机构信息

Department of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, P.M.B. 12003, Lagos.

出版信息

Afr J Tradit Complement Altern Med. 2006 Nov 13;4(2):191-8. doi: 10.4314/ajtcam.v4i2.31207.

Abstract

There is increasing resistance of malaria parasites to chloroquine, the cheapest and commonly used drug for malaria in Nigeria. Artemisin, a product from medicinal plant indigenous to China, based on active principle of Artemisia annua, has been introduced into the Nigerian market. However not much has been done to project antimalaria properties of indigenous medicinal plants. This study thus, has the main objective of presenting medicinal plants used for malaria therapy in Okeigbo, Ondo State, South west Nigeria. Focus group discussions and interview were held about plants often found useful for malaria therapy in the community. Fifty species (local names) including for example: Morinda lucida (Oruwo), Enantia chlorantha (Awopa), Alstonia boonei (Ahun), Azadirachta indica (Dongoyaro) and Khaya grandifoliola (Oganwo) plants were found to be in use for malaria therapy at Okeigbo, Southwest, Nigeria . The parts of plants used could either be the barks, roots, leaves or whole plants. The recipes also, could be a combination of various species of plants or plant parts. This study highlights potential sources for the development of new antimalarial drugs from indigenous medicinal plants found in Okeigbo, Nigeria.

摘要

疟原虫对氯喹的耐药性日益增强,氯喹是尼日利亚治疗疟疾最便宜且常用的药物。基于青蒿活性成分的青蒿素,一种源自中国本土药用植物的产品,已被引入尼日利亚市场。然而,在宣传本土药用植物的抗疟特性方面所做的工作不多。因此,本研究的主要目的是介绍尼日利亚西南部翁多州奥凯格博用于疟疾治疗的药用植物。就社区中常用于疟疾治疗的植物进行了焦点小组讨论和访谈。发现有五十种(当地名称)植物,例如:亮叶巴戟(奥鲁沃)、非洲臀果木(阿沃帕)、布氏鸡骨常山(阿洪)、印楝(东戈亚罗)和大叶卡雅楝(奥甘沃)等植物在尼日利亚西南部的奥凯格博被用于疟疾治疗。所使用的植物部位可以是树皮、根、叶或整株植物。配方也可以是多种植物或植物部位的组合。本研究突出了尼日利亚奥凯格博发现的本土药用植物作为开发新型抗疟药物潜在来源的可能性。

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本文引用的文献

1
Pitfalls in a discovery: the chronicle of chloroquine.一项发现中的陷阱:氯喹纪事
Am J Trop Med Hyg. 1963 Mar;12:121-8. doi: 10.4269/ajtmh.1963.12.121.
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Chloroquine-resistant falciparum malaria in Madagascar and Kenya.马达加斯加和肯尼亚的氯喹耐药恶性疟
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Chloroquine-resistant Plasmodium falciparum malaria in Kenya.肯尼亚的氯喹耐药恶性疟原虫疟疾
Trans R Soc Trop Med Hyg. 1979;73(2):228-9. doi: 10.1016/0035-9203(79)90220-7.

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