Ukabam C U
Department of Physiology, University of Bristol Medical School.
Ric Clin Lab. 1988 Oct-Dec;18(4):313-8. doi: 10.1007/BF02919089.
Morphological studies on the hypoglossal nucleus of 'wobbler' and control mice were carried out using the Golgi-Cox technique. In 'wobbler' mice, soma and dendrites of degenerating neurons were swollen and less darkly stained when compared with normal neurons; in addition, their membrane structure was disrupted. Neurons could not be distinguished by their shape, as they varied greatly. Using dendritic directional projections, neurons were classified into four main groups. In the normal mouse, three main classes of neurons are apparent, i.e., large, intermediate and small neurons measuring on the average 25, 16 and 9.5 mu, respectively. In the 'wobbler' sections, about 11 degenerating neurons with diameters ranging from 35 to 50 mu were clearly identified.
采用高尔基-考克斯技术对“摇摆病”小鼠和对照小鼠的舌下神经核进行了形态学研究。在“摇摆病”小鼠中，与正常神经元相比，退化神经元的胞体和树突肿胀，染色较浅；此外，它们的膜结构被破坏。神经元的形状差异很大，无法通过形状来区分。利用树突的定向投射，将神经元分为四个主要组。在正常小鼠中，有三种主要类型的神经元，即大神经元、中神经元和小神经元，平均直径分别为25微米、16微米和9.5微米。在“摇摆病”小鼠的切片中，清晰地识别出约11个直径在35至50微米之间的退化神经元。
