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色素沉着绒毛结节性滑膜炎

[Pigmented villonodular synovitis].

作者信息

Court S, Nissen M J, Gabay C

出版信息

Rev Med Suisse. 2014 Mar 12;10(421):609-10, 612, 614-5.

Abstract

Pigmented villonodular synovitis (PVNS), also known as tenosynovial giant cell tumour is an articular pathology that occurs predominantly in young adults and is caused by an abnormal proliferation of the synovial membrane. The clinical presentation includes pain and joint swelling. MRI represents the best imaging modality to investigate this disease but the histopathology of synovial tissue provides the definitive diagnosis. The management of PVNS is often difficult due to the high risk of relapse after treatment. The objective of this article is to review the literature regarding the diagnosis and therapy of this poorly understood condition.

摘要

色素沉着绒毛结节性滑膜炎(PVNS),也称为腱鞘巨细胞瘤,是一种主要发生于年轻人的关节病变,由滑膜异常增殖引起。临床表现包括疼痛和关节肿胀。磁共振成像(MRI)是检查该疾病的最佳影像学方法,但滑膜组织的组织病理学检查可提供明确诊断。由于PVNS治疗后复发风险高,其治疗往往具有挑战性。本文的目的是综述关于这种了解甚少的疾病的诊断和治疗的文献。

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