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CD133 might be a pan marker of epithelial cells with dedifferentiation capacity.CD133可能是具有去分化能力的上皮细胞的一种泛标志物。
Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1451-2. doi: 10.1073/pnas.1400195111. Epub 2014 Mar 20.
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Improved differentiation of human enriched CD133+CD24 renal progenitor cells derived from embryonic stem cell with embryonic mouse kidney-derived mesenchymal stem cells co-culture.与人胚胎干细胞来源的富集 CD133+CD24 肾祖细胞共培养的胚胎鼠肾间充质干细胞可改善其分化。
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[Influence and distribution of CD133 and CD34 antigen expression in proximal tubule epithelial cells during ischemia/reperfusion injury in rats].[大鼠缺血/再灌注损伤时近端肾小管上皮细胞中CD133和CD34抗原表达的影响及分布]
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Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133?突起小体——一类含有prominin-1/CD133的特殊细胞外囊泡?
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Renal tubular epithelial cells response to injury in acute kidney injury.急性肾损伤中肾小管上皮细胞对损伤的反应。
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Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma.利用 CD133 特异性嵌合抗原受体 T 细胞通过非病毒 Sleeping Beauty 转座实现 PD-1 阻断 scFv 的靶向递送,显著提高晚期肝细胞癌的抗肿瘤疗效。
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Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation.周期蛋白 G1 通过激活 CDK5 诱导适应性近端肾小管细胞去分化和肾纤维化。
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Novel leukocyte-depleted platelet-rich plasma-based skin equivalent as an in vitro model of chronic wounds: a preliminary study.新型去白细胞富血小板血浆基皮肤等效物作为慢性创面的体外模型:初步研究。
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Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation.体细胞、人类多能干细胞及其衍生物的全球免疫相关基因谱比较:对人类淋巴细胞增殖的影响。
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CD133-Positive Membrane Particles in Cerebrospinal Fluid of Patients with Inflammatory and Degenerative Neurological Diseases.炎症性和退行性神经疾病患者脑脊液中CD133阳性膜微粒
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本文引用的文献

1
Differentiated kidney epithelial cells repair injured proximal tubule.分化的肾上皮细胞修复受损的近端肾小管。
Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1527-32. doi: 10.1073/pnas.1310653110. Epub 2013 Oct 14.
2
CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells.CD133 是造血祖细胞频率的调节剂,但对于维持小鼠造血干细胞则不是必需的。
Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5582-7. doi: 10.1073/pnas.1215438110. Epub 2013 Mar 18.
3
Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer.Prominin-1/CD133是一种神经和造血干细胞标志物,在成人分化细胞和某些类型的肾癌中表达。
Cell Tissue Res. 2005 Jan;319(1):15-26. doi: 10.1007/s00441-004-1018-z. Epub 2004 Nov 19.
4
Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis.具有可变C末端的新型Prominin-1/CD133剪接变体的鉴定及其在附睾和睾丸中的表达。
J Cell Sci. 2004 Aug 15;117(Pt 18):4301-11. doi: 10.1242/jcs.01315.
5
Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells.Prominin是一种上皮细胞顶端表面新的微绒毛特异性多跨膜蛋白,定位于非上皮细胞的质膜突起处。
Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12425-30. doi: 10.1073/pnas.94.23.12425.

CD133 might be a pan marker of epithelial cells with dedifferentiation capacity.

作者信息

Corbeil Denis, Fargeas Christine A, Jászai József

机构信息

Tissue Engineering Laboratories (BIOTEC) and Institute of Anatomy, Medizinische Fakultät der Technische Universität Dresden, 01307 Dresden, Germany.

出版信息

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1451-2. doi: 10.1073/pnas.1400195111. Epub 2014 Mar 20.

DOI:10.1073/pnas.1400195111
PMID:24706908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3992674/
Abstract
摘要