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富含血小板血浆辅助一名40岁男性伴有根尖周病变的未成熟牙齿的血管再生。

Platelet-rich plasma supplemented revascularization of an immature tooth associated with a periapical lesion in a 40-year-old man.

作者信息

Jadhav Ganesh Ranganath, Shah Naseem, Logani Ajay

机构信息

Department of Conservative Dentistry and Endodontics, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi 110029, India.

出版信息

Case Rep Dent. 2014;2014:479584. doi: 10.1155/2014/479584. Epub 2014 Feb 20.

DOI:10.1155/2014/479584
PMID:24707409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3965948/
Abstract

The present case report is the first of its kind that documents the successful outcome of "revascularization," a regeneration-based treatment protocol in a mature adult patient. It belies the myth that "revascularization" should only be done in children and young, adolescent patients. The misconception that stem cells number as well as viability in older age group patients will not allow revascularization to be successful is also contradicted by this case. The paper highlights all the mechanisms that come into play and the enhancing of regenerative response by supplementation with platelet-rich plasma (PRP).

摘要

本病例报告首次记录了“血管再生”这种基于再生的治疗方案在成年患者身上取得的成功结果。它打破了“血管再生”仅应在儿童和青少年患者中进行的神话。本病例也反驳了老年患者干细胞数量和活力不允许血管再生成功的错误观念。该论文强调了所有发挥作用的机制以及通过补充富血小板血浆（PRP）增强再生反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3017/3965948/c77caf57b5b6/CRID2014-479584.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3017/3965948/c77caf57b5b6/CRID2014-479584.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3017/3965948/c77caf57b5b6/CRID2014-479584.001.jpg

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本文引用的文献

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Treatment options: biological basis of regenerative endodontic procedures.治疗方案：再生牙髓治疗的生物学基础。
J Endod. 2013 Mar;39(3 Suppl):S30-43. doi: 10.1016/j.joen.2012.11.025.
2
Revascularization with and without platelet-rich plasma in nonvital, immature, anterior teeth: a pilot clinical study.非活力、未成熟前牙中应用和不应用富含血小板血浆的血运重建：一项初步临床研究。
J Endod. 2012 Dec;38(12):1581-7. doi: 10.1016/j.joen.2012.09.010. Epub 2012 Oct 23.
3
Platelet Rich Fibrin in the revitalization of tooth with necrotic pulp and open apex.
使用富血小板纤维蛋白支架评估未萌恒切牙的再生潜能的前瞻性队列研究。
Sci Rep. 2021 Jul 1;11(1):13679. doi: 10.1038/s41598-021-93236-2.
4
Management of necrotic immature permanent maxillary incisors using a modified technique of revascularisation.采用改良的牙髓血管再生技术治疗坏死的未成熟恒上颌切牙
BMJ Case Rep. 2021 Mar 17;14(3):e240203. doi: 10.1136/bcr-2020-240203.
5
Scaffolds in regenerative endodontics: A review.再生牙髓病学中的支架：综述
Dent Res J (Isfahan). 2016 Sep;13(5):379-386. doi: 10.4103/1735-3327.192266.
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Decoding of disinfection regime used in revascularization.血管重建术中使用的消毒方案解码。
J Nat Sci Biol Med. 2016 Jan-Jun;7(1):113-4. doi: 10.4103/0976-9668.175109.
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J Nat Sci Biol Med. 2015 Jan-Jun;6(1):224-5. doi: 10.4103/0976-9668.149187.
富血小板纤维蛋白在坏死牙髓及根尖孔开放牙齿的牙髓再生中的应用
J Conserv Dent. 2012 Oct;15(4):395-8. doi: 10.4103/0972-0707.101926.
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Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth.关于在恒牙未成熟受创牙中应用牙髓再生术的建议。
Dent Traumatol. 2012 Feb;28(1):33-41. doi: 10.1111/j.1600-9657.2011.01044.x. Epub 2011 Jul 27.
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J Endod. 2011 Aug;37(8):1109-15. doi: 10.1016/j.joen.2011.05.013.
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J Endod. 2011 Feb;37(2):133-8. doi: 10.1016/j.joen.2010.10.009.
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Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report.与三联抗生素治疗相关的未成熟恒切牙牙齿变色：病例报告。
J Endod. 2010 Jun;36(6):1086-91. doi: 10.1016/j.joen.2010.03.031.
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Challenges in regenerative endodontics: a case series.再生牙髓学的挑战：病例系列。
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