Qureshi Muhammad Omar, Dar Faisal Saud, Khokhar Nasir
Department of Gastroenterology, Shifa International Hospital, Islamabad.
J Coll Physicians Surg Pak. 2014 Apr;24(4):232-5.
To evaluate the correlation between Cancer Antigen-25 (CA-125) levels with the amount of ascites in patients with liver cirrhosis.
Observational, analytical study.
Shifa International Hospital, Islamabad, from March 2012 to February 2013.
A total of 130 patients with liver cirrhosis (with and without ascites) had serum CA-125 levels measured. The amount of ascites was classified according to physical examination and ultrasound (USG) findings. CA-125 levels were compared and correlated with amount of ascites.
Majority of patients (57%) had hepatitis C virus and 60% were in class Child Pugh C. There was moderate correlation between amount of ascites and CA-125 levels (r = 0.642, p < 0.001) with significant raised levels of CA-125 in patients with ascites (p < 0.001).
There was a moderate correlation between CA-125 levels and presence and amount of ascites.
评估肝硬化患者癌抗原25（CA - 125）水平与腹水量之间的相关性。
观察性分析研究。
2012年3月至2013年2月，伊斯兰堡的希法国际医院。
共对130例肝硬化患者（有腹水和无腹水）进行血清CA - 125水平检测。根据体格检查和超声（USG）检查结果对腹水量进行分类。比较CA - 125水平并与腹水量进行相关性分析。
大多数患者（57%）感染丙型肝炎病毒，60%为Child - Pugh C级。腹水量与CA - 125水平之间存在中度相关性（r = 0.642，p < 0.001），腹水患者的CA - 125水平显著升高（p < 0.001）。
CA - 125水平与腹水的存在及腹水量之间存在中度相关性。
