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消除冈比亚型人类非洲锥虫病的征程:路途不远,但并不轻松。

The journey towards elimination of gambiense human African trypanosomiasis: not far, nor easy.

作者信息

Franco J R, Simarro P P, Diarra A, Ruiz-Postigo J A, Jannin J G

机构信息

World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, 20, Av. Appia, 1211 Geneva, Switzerland.

World Health Organization, WHO Inter Country Support Team for Central Africa, Regional Office for Africa, IST/CA, BP 820, Libreville, Gabon.

出版信息

Parasitology. 2014 May;141(6):748-60. doi: 10.1017/S0031182013002102.

DOI:10.1017/S0031182013002102
PMID:24709291
Abstract

Considering the epidemic situation of gambiense human African trypanosomiasis (HAT) at the end of the twentieth century, the World Health Organization (WHO) and partners strengthened disease control and surveillance. Over the last 15 years, the activities implemented through the National Control Programmes have brought gambiense HAT under control and now its elimination is deemed as an achievable goal. In 2012, WHO targeted gambiense HAT for elimination as a public health problem by 2020. The final goal will be the sustainable disease elimination by 2030, defined as the interruption of the transmission of gambiense HAT. The elimination is considered feasible, because of the epidemiological vulnerability of the disease, the current state of control, the availability of strategies and tools and international commitment and political will. Integration of activities in the health system is needed to ensure the sustainability of the elimination. The development of user-friendly diagnostic and treatment tools will facilitate the integration process. Adequate funding is needed to implement activities, but also to support research that will make the elimination sustainable. A long-term commitment by donors is needed and ownership of the process by endemic countries is critical.

摘要

考虑到20世纪末冈比亚型人类非洲锥虫病(HAT)的疫情,世界卫生组织(WHO)及其合作伙伴加强了疾病控制和监测。在过去15年里,通过国家控制规划开展的活动已使冈比亚型HAT得到控制,目前认为消除该疾病是一个可实现的目标。2012年,WHO将到2020年消除冈比亚型HAT作为一个公共卫生问题作为目标。最终目标是到2030年实现该疾病的可持续消除,定义为冈比亚型HAT传播的中断。由于该疾病的流行病学脆弱性、当前的控制状态、战略和工具的可用性以及国际承诺和政治意愿,消除被认为是可行的。需要将各项活动纳入卫生系统,以确保消除工作的可持续性。开发方便用户的诊断和治疗工具将促进整合过程。实施各项活动不仅需要充足的资金,还需要支持有助于实现可持续消除的研究。捐助方需要做出长期承诺,流行国家对这一进程的自主掌控至关重要。

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