Guo Rui, Li Kang-Nan, Liu Bin, Zhu Hua-Jie, Fan Yu-Meng, Gong Liu-Zhu
Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
Chem Commun (Camb). 2014 May 28;50(41):5451-4. doi: 10.1039/c4cc01397b.
The chiral gold(i) complex enables enantioselective cycloisomerization-amination of 2-(alkynyl)phenyl boronic acids and diazenes in high yields. A wide scope of substrates bearing various functional groups was tolerated to generate structurally different hydrazide derivatives as a new type of atropisomer.
手性金（I）配合物能够实现2-（炔基）苯基硼酸与重氮化合物的对映选择性环异构化胺化反应，产率很高。带有各种官能团的多种底物都能被耐受，从而生成结构不同的酰肼衍生物，作为一种新型的阻转异构体。
