Azuero Andres, Benz Rachel, McNees Patrick, Meneses Karen
School of Nursing, University of Alabama at Birmingham, NB 1019G - 1720 2nd AVE S, Birmingham, AL 35294-1210 USA.
School of Nursing, University of Alabama at Birmingham, NB 1020 - 1720 2nd AVE S, Birmingham, AL 35294-1210 USA.
Springerplus. 2014 Feb 20;3:102. doi: 10.1186/2193-1801-3-102. eCollection 2014.
More than 66% of the 200,000 newly diagnosed annual breast cancers in the US occurs in women over 55 years. Treatment advances result in excellent survival, yet older breast cancer survivors with co-morbidity may live longer, but not better after cancer. Decline in physical function, increased social isolation, and diminished economic resources increase vulnerability among older women. Rural women represent an underserved population. The purpose is to examine associations between comorbidity and predictors of health status among older rural breast cancer survivors.
Baseline data of 331 BCS age 55-90 years enrolled in the Rural Breast Cancer Survivors Study. Four surveys were used for data collection. Self-reported prescription medications were used as proxy for co-morbidity. Bivariate tests of association and multivariable recursive partitioning techniques were used for analysis.
Mean number of prescription medication categories reported was 3.68 (SD = 2.3; range = 0-12). Common prescription categories were: anti-hormonal, anti-hypertensive, and cholesterol- reducing agents. 69% was overweight or obese. BMI >31 was significantly associated with both poorer physical and mental health. Multivariate analyses indicated physical health status was predicted by BMI, comorbid conditions, social support, and adverse changes in economic lifestyle. The same variables, with the exception of BMI, were predictors of mental health status.
Assessing co-morbid conditions, mental health status, social support, and economic burden after breast cancer treatment may better inform cancer survivorship care and comprehensive geriatric assessment.
在美国每年新诊断出的20万例乳腺癌病例中，超过66%发生在55岁以上的女性身上。治疗方法的进步带来了出色的生存率，然而患有合并症的老年乳腺癌幸存者可能活得更长，但癌症后的生活质量并未提高。身体功能下降、社会隔离增加以及经济资源减少，使老年女性更加脆弱。农村女性是服务不足的人群。目的是研究老年农村乳腺癌幸存者的合并症与健康状况预测因素之间的关联。
纳入农村乳腺癌幸存者研究的331名年龄在55 - 90岁之间的乳腺癌幸存者的基线数据。使用四项调查进行数据收集。自我报告的处方药被用作合并症的替代指标。采用双变量关联检验和多变量递归划分技术进行分析。
报告的处方药类别平均数量为3.68（标准差 = 2.3；范围 = 0 - 12）。常见的处方药类别有：抗激素药、抗高血压药和降胆固醇药。69%的人超重或肥胖。BMI > 31与较差的身心健康均显著相关。多变量分析表明，身体健康状况由BMI、合并症、社会支持和经济生活方式的不利变化预测。除BMI外，相同的变量是心理健康状况的预测因素。
评估乳腺癌治疗后的合并症、心理健康状况、社会支持和经济负担，可能会为癌症幸存者护理和综合老年评估提供更好的信息。
