Ridner Sheila H, Dietrich Mary S
School of Nursing, Vanderbilt University, Nashville, TN, USA.
Oncol Nurs Forum. 2008 Jan;35(1):57-63. doi: 10.1188/08.ONF.57-63.
PURPOSE/OBJECTIVES: To compare the self-reported comorbid conditions and medication usage between breast cancer survivors with and without breast cancer treatment-related lymphedema.
Descriptive, cross-sectional.
A community-based study conducted in a major metropolitan area and surrounding rural counties in the southeastern United States.
A convenience sample of 64 breast cancer survivors with lymphedema and 64 breast cancer survivors without lymphedema who were age matched within three years and recruited for a parent study. Twenty-one additional non-age-matched breast cancer survivors with or without lymphedema also were included.
Self-reported survey instruments and height and weight measurement.
Lymphedema, demographic information, self-reported comorbid diseases or medical issues, and medication usage.
Breast cancer survivors with lymphedema experienced more comorbid conditions. Statistically significant group differences were found in body mass index, orthopedic issues, cardiac medications, hormone blockers, and osteoporosis medication or calcium supplement usage. Co-occurrence of diabetes and carpal tunnel syndrome approached statistical significance. Breast cancer survivors with lymphedema were older and had lower incomes.
Comorbid conditions may influence the development of breast cancer treatment-related lymphedema. Further research, particularly a longitudinal study, is indicated.
Healthcare professionals who care for breast cancer survivors need to routinely assess them for the presence of comorbid conditions and the development of lymphedema. Obese breast cancer survivors may benefit from weight reduction interventions to possibly decrease their risk of developing lymphedema and improve their overall health status. Patients with arthritis and orthopedic and cardiac issues such as hypertension may warrant careful monitoring.
目的/目标：比较有和没有乳腺癌治疗相关淋巴水肿的乳腺癌幸存者自我报告的合并症及药物使用情况。
描述性横断面研究。
在美国东南部一个主要大都市地区及周边农村县进行的一项基于社区的研究。
64名有淋巴水肿的乳腺癌幸存者和64名无淋巴水肿的乳腺癌幸存者组成的便利样本，这些幸存者年龄在三年内匹配，并被纳入一项母研究。另外还纳入了21名年龄不匹配的有或无淋巴水肿的乳腺癌幸存者。
自我报告调查工具以及身高和体重测量。
淋巴水肿、人口统计学信息、自我报告的合并疾病或医疗问题以及药物使用情况。
有淋巴水肿的乳腺癌幸存者合并症更多。在体重指数、骨科问题、心脏药物、激素阻滞剂以及骨质疏松症药物或钙补充剂的使用方面发现了具有统计学意义的组间差异。糖尿病和腕管综合征的共现接近统计学意义。有淋巴水肿的乳腺癌幸存者年龄更大且收入更低。
合并症可能会影响乳腺癌治疗相关淋巴水肿的发生。需要进一步研究，尤其是纵向研究。
照顾乳腺癌幸存者的医护人员需要定期评估他们是否存在合并症以及淋巴水肿的发生情况。肥胖的乳腺癌幸存者可能会从减重干预中受益，这可能会降低他们发生淋巴水肿的风险并改善其整体健康状况。患有关节炎以及骨科和心脏问题（如高血压）的患者可能需要仔细监测。
