Goudot P, Auriol M, Chomette G, Vaillant J M, Guilbert F
Institut de Stomatologie et de Chirurgie Maxillo-faciale, Hôpital de la Pitié-Salpêtrière, Paris.
Rev Stomatol Chir Maxillofac. 1989;90(2):119-22.
In a series of 570 pleomorphic adenomas of main and accessory salivary glands, we found 48 recurrences (8.04%). These recurrences occurred between several months and 19 years after surgical treatment. They were more frequently noted in parotid tumors. Comparatively to a control series, in recurrent tumors myxoid structures were more frequent than epithelial structures, as demonstrated by immuno-markings (anti-protein S 100 and anti-vimentin sera). Besides, in these tumors, extracapsular myxoid expansions were commonly seen. The proliferative potential of myoepithelial cells which are the main cellular component of myxoid areas, is thus suggested as a mainly factor of recurrence of pleomorphic adenomas.
