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在一家大型肝胰胆学术中心进行肝切除术后的再入院发生率及相关因素。

Readmission incidence and associated factors after a hepatic resection at a major hepato-pancreatico-biliary academic centre.

作者信息

Spolverato Gaya, Ejaz Aslam, Kim Yuhree, Weiss Mattew, Wolfgang Christopher L, Hirose Kenzo, Pawlik Timothy M

机构信息

Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

HPB (Oxford). 2014 Nov;16(11):972-8. doi: 10.1111/hpb.12262. Epub 2014 Apr 9.

DOI:10.1111/hpb.12262
PMID:24712690
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4487747/
Abstract

BACKGROUND

Reducing readmission is a key quality improvement target for policymakers. The purpose of the present study was to define incidence and identify factors associated with readmission after a hepatic resection.

METHODS

Thirty-day readmission after discharge and factors associated with a higher risk of readmission were examined among patients undergoing a hepatic resection at Johns Hopkins Hospital between 2008 and 2012.

RESULTS

Among the 338 patients, the median age was 57.9 years and 173 (51.2%) were men. Indications for surgery included colorectal cancer liver metastasis (38.2%), primary hepatic tumours (25.7%) and benign disease (3.3%). Surgical resection consisted of less than a hemi-hepatectomy in the majority of patients (n = 224, 66.3%). The median index hospitalization length-of-stay (LOS) was 5 days; 68.7% patients experienced at least one inpatient complication. Overall 30-day readmission was 14.2% (n = 48). The majority of readmitted patients (n = 46, 95.8%) had a complication prior to readmission. The median LOS for readmission was 4 [interquartile range (IQR) 2-6] days. On multivariable analysis, the strongest independent predictor of readmission was the presence of a major complication [odds ratio (OR) 5.30, 95% confidence interval (CI) 2.38-11.78, P < 0.001].

CONCLUSIONS

Readmission after a hepatic resection occurs in approximately one out of every seven patients. Patients who experience a post-operative complication are greater than five times more likely to be readmitted. Prospective studies are needed to evaluate methods to reduce unplanned readmissions.

摘要

背景

降低再入院率是政策制定者提高医疗质量的关键目标。本研究的目的是确定肝切除术后再入院的发生率,并识别与之相关的因素。

方法

对2008年至2012年间在约翰霍普金斯医院接受肝切除手术的患者进行了出院后30天再入院情况及与再入院高风险相关因素的调查。

结果

338例患者中,年龄中位数为57.9岁,男性173例(51.2%)。手术指征包括结直肠癌肝转移(38.2%)、原发性肝肿瘤(25.7%)和良性疾病(3.3%)。大多数患者(n = 224,66.3%)的手术切除范围小于半肝切除。首次住院的中位住院时长(LOS)为5天;68.7%的患者至少发生过一次住院并发症。总体30天再入院率为14.2%(n = 48)。大多数再入院患者(n = 46,95.8%)在再入院前出现过并发症。再入院的中位LOS为4[四分位间距(IQR)2 - 6]天。多变量分析显示,再入院最强的独立预测因素是存在严重并发症[比值比(OR)5.30,95%置信区间(CI)2.38 - 11.78,P < 0.001]。

结论

肝切除术后约七分之一的患者会再次入院。术后出现并发症的患者再次入院的可能性高出五倍多。需要进行前瞻性研究以评估降低非计划再入院率方法。

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